Results 11 to 20 of about 68,515 (215)
Pathogens, 2022 Removal of genes coding for major parts of capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts the production of infectious virus particles where the remaining genome forms a replicon that retains replicability in ...
Pham-Tue-Hung Tran +6 more
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Microorganisms, 2020 Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). The virus has a single-strand positive-sense RNA genome that encodes a polyprotein.
Pham-Tue-Hung Tran +7 more
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NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity
Frontiers in Immunology, 2023 Micro- and nanoplastics (MNPs) are emerging pollutants with scarcely investigated effects on human innate immunity. If they follow a similar course of action as other, more thoroughly investigated particulates, MNPs may penetrate epithelial barriers ...
Andi Alijagic +10 more
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From bench to bedside: Calprotectin (S100A8/S100A9) as a biomarker in rheumatoid arthritis
Frontiers in Immunology, 2022 S100A9/S100A8 (calprotectin), a member of the S100 protein family, has been shown to play a pivotal role in innate immunity activation. Calprotectin plays a critical role in the pathogenesis of rheumatoid arthritis (RA), as it triggers chemotaxis ...
José Inciarte-Mundo +3 more
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The inflammatory response in stroke [PDF]
Journal of Neuroimmunology, 2007 Recent works in the area of stroke and brain ischemia has demonstrated the significance of the inflammatory response accompanying necrotic brain injury. Acutely, this response appears to contribute to ischemic pathology, and anti-inflammatory strategies have become popular. This chapter will discuss the current knowledge of the contribution of systemic
Qing, Wang +2 more
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Frontiers in Toxicology, 2022 Additive manufacturing (AM) or industrial three-dimensional (3D) printing drives a new spectrum of design and production possibilities; pushing the boundaries both in the application by production of sophisticated products as well as the development of ...
Andi Alijagic +18 more
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Clinical & Translational Immunology, 2021 Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers.
Zeinab Dalloul +14 more
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Serotype-Specific Killing of Large Cell Carcinoma Cells by Reovirus
Viruses, 2017 Reovirus is under development as a therapeutic for numerous types of cancer. In contrast to other oncolytic viruses, the safety and efficacy of reovirus have not been improved through genetic manipulation.
Emily J. Simon +3 more
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Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent
Journal of Immunology Research, 2019 Meningococcal disease such as sepsis and meningitidis is hallmarked by an excessive inflammatory response. The causative agent, Neisseria meningitidis, expresses the endotoxin lipooligosaccharide (LOS) that is responsible for activation of immune cells ...
Berhane Asfaw Idosa +6 more
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Natural killer (NK) cell-derived extracellular-vesicle shuttled microRNAs control T cell responses
eLife, 2022 Natural killer (NK) cells recognize and kill target cells undergoing different types of stress. NK cells are also capable of modulating immune responses. In particular, they regulate T cell functions.
Sara G Dosil +12 more
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