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This chapter describes the pathology of inflammatory response as it applies to Emergency Medicine, and in particular the Primary FRCEM examination. The chapter outlines the key details of normal vs abnormal response, and inflammatory markers including C-reactive protein, rheumatoid factor, and antinuclear factor.
Mark Harrison
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The inflammatory response in stroke [PDF]
Recent works in the area of stroke and brain ischemia has demonstrated the significance of the inflammatory response accompanying necrotic brain injury. Acutely, this response appears to contribute to ischemic pathology, and anti-inflammatory strategies have become popular. This chapter will discuss the current knowledge of the contribution of systemic
Qing, Wang +2 more
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Spontaneous one-lung ventilation increases the lung inflammatory response : an experimental pilot study [PDF]
Study objective: The purpose of this study was to investigate if spontaneous one-lung ventilation would induce any type of inflammatory lung response when compared to spontaneous two-lung ventilation and its intensity, by quantification of inflammatory ...
Nunes, Catarina S. +5 more
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Inflammatory response and the endothelium [PDF]
Antiphospholipid-mediated endothelium perturbation plays a role in antiphospholipid syndrome (APS)-associated vasculopathy. Antiphospholipid antibodies activate endothelium both in vitro and in vivo experimental models by inducing a pro-inflammatory/-coagulant phenotype; the antibodies recognize beta2 glycoprotein I (beta2GPI) on human endothelial ...
P.L. Meroni +11 more
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NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity
Micro- and nanoplastics (MNPs) are emerging pollutants with scarcely investigated effects on human innate immunity. If they follow a similar course of action as other, more thoroughly investigated particulates, MNPs may penetrate epithelial barriers ...
Andi Alijagic +10 more
doaj +1 more source
From bench to bedside: Calprotectin (S100A8/S100A9) as a biomarker in rheumatoid arthritis
S100A9/S100A8 (calprotectin), a member of the S100 protein family, has been shown to play a pivotal role in innate immunity activation. Calprotectin plays a critical role in the pathogenesis of rheumatoid arthritis (RA), as it triggers chemotaxis ...
José Inciarte-Mundo +3 more
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Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
Anderson, George +34 more
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Albumin concentrations are primarily determined by the body cell mass and the systemic inflammatory response in cancer patients with weight loss [PDF]
The association between hypoalbuminemia and poor prognosis in patients with cancer is well recognized. However, the factors that contribute to the fall in albumin concentrations are not well understood.
Watson, W.S. +5 more
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Inflammatory markers: An Overview
Inflammation is the body’s innate response to injury or insult, including infection, trauma, surgery, burns, and cancer. Certain proteins are released into the bloodstream during inflammation; if their concentrations increase or decrease by at least 25%,
Inflammatory markers: An Overview
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Additive manufacturing (AM) or industrial three-dimensional (3D) printing drives a new spectrum of design and production possibilities; pushing the boundaries both in the application by production of sophisticated products as well as the development of ...
Andi Alijagic +18 more
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