Results 31 to 40 of about 22,373 (186)

<i>Parabacteroides goldsteinii</i> mitigates the lipopolysaccharide-induced inflammatory response in IPEC-J2 cells. [PDF]

open access: yesFront Vet Sci
IntroductionThe misuse of antibiotics threatens animal health and food safety and limits the development of livestock and poultry farming. In animal husbandry, probiotics can be used as an alternative to antibiotics because of their environmental protection and high efficiency.
Zhang J   +6 more
europepmc   +4 more sources

Effects of Different Methionine Sources on Methionine Metabolism in the IPEC-J2 Cells [PDF]

open access: yesBioMed Research International, 2019
As one of the essential amino acids, methionine (Met) plays an important role in biological events such as methylation and antioxidant properties besides its function in protein synthesis. Different Met sources have been used in animal production, but their effects on Met metabolic pathways are not well understood. In the present study, we investigated
Fangrui Zuo   +4 more
openaire   +2 more sources

Vitamin K Vitamers Differently Affect Energy Metabolism in IPEC-J2 Cells [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
The fat-soluble vitamin K (VK) has long been known as a requirement for blood coagulation, but like other vitamins, has been recently recognized to play further physiological roles, particularly in cell development and homeostasis. Vertebrates cannot de novo synthesize VK, which is essential, and it can only be obtained from the diet or by the activity
Chiara Bernardini   +7 more
openaire   +4 more sources

lnc001776 Affects CPB2 Toxin-Induced Excessive Injury of Porcine Intestinal Epithelial Cells via Activating JNK/NF-kB Pathway through ssc-let-7i-5p/IL-6 Axis

open access: yesCells, 2023
Piglet diarrhea caused by Clostridium perfringens (C. perfringens) type C (CpC) seriously endangers the development of the pig production industry. C. perfringens beta2 (CPB2) toxin is a virulent toxin produced by CpC.
Kaihui Xie   +7 more
doaj   +1 more source

STIM1 promotes IPEC-J2 porcine epithelial cell restitution by TRPC1 signaling

open access: yesAnimal Biotechnology, 2021
Intestinal epithelial restitution is partly dependent on cell migration, which reseals superficial wounding after injury. Here, we tested the hypothesis that stromal interaction molecule 1(STIM1) regulates porcine intestinal epithelial cell migration by activating transient receptor potential canonical 1 (TRPC1) signaling.
Weiwei Mo   +6 more
openaire   +2 more sources

Profiling of alternative polyadenylation and gene expression in PEDV-infected IPEC-J2 cells [PDF]

open access: yesVirus Genes, 2021
Since 2010, porcine epidemic diarrhea virus (PEDV) has received global attention with the emergence of variant strains characterized with high pathogenicity. The pathogen-host interaction after PEDV infection is still unclear. To investigate this issue, high-throughput-based sequencing technology is one of the optimal choices. In this study, we used in
Xiaona Wei   +5 more
openaire   +2 more sources

Growth behavior and mRNA expression profiling during growth of IPEC-J2 cells. [PDF]

open access: yesBMC Res Notes
Abstract Objective The IPEC-J2 cell line is used as an in vitro small intestine model for swine, but it is also used as a model for the human intestine, presenting a relatively unique setting. By combining electric cell-substrate impedance sensing, with next-generation-sequencing technology, we showed that mRNA gene ...
Binder ARD   +3 more
europepmc   +4 more sources

β-defensin 118 attenuates inflammation and injury of intestinal epithelial cells upon enterotoxigenic Escherichia coli challenge

open access: yesBMC Veterinary Research, 2022
Background Antimicrobial peptides including various defensins have been attracting considerable research interest worldwide, as they have potential to substitute for antibiotics. Moreover, AMPs also have immunomodulatory activity.
Qingqing Fu   +11 more
doaj   +1 more source

Activation of the JNK/MAPK Signaling Pathway by TGF-β1 Enhances Neonatal Fc Receptor Expression and IgG Transcytosis

open access: yesMicroorganisms, 2021
The neonatal Fc receptor (FcRn) transports maternal immunoglobulin G (IgG) to the foetus or newborn and protects the IgG from degradation. FcRn is expressed in several porcine tissues and cell types and its expression levels are regulated by immune and ...
Shaoju Qian   +5 more
doaj   +1 more source

JNK molecule is a toxic target for IPEC-J2 cell barrier damage induced by T-2 toxin

open access: yesEcotoxicology and Environmental Safety, 2023
The most prevalent contaminated mycotoxin in feed and grain is T-2 toxin. The T-2 toxin's primary action target is the gut because it is the main organ of absorption.
Fengjuan Chen   +6 more
doaj   +1 more source

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