Results 51 to 60 of about 22,373 (186)
, 2021 Clostridium perfringens (C. perfringens) causes intestinal injury through overgrowth and the secretion of multiple toxins, leading to diarrhea and necrotic enteritis in animals, including pigs, chickens, and sheep.
Zihan Zeng +8 more
core +1 more source
Entry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis
Virology Journal, 2019 Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, are a significant cause of enteritis, pneumonia, polioencephalomyelitis and reproductive disorders in pigs. However, the life cycle of PSV on the molecular level is largely unknown.Here, we used chemical inhibitors, RNA interference, and overexpression of ...
Tingting Zhao +5 more
openaire +3 more sources
Protective Effects of Ferulic Acid on Deoxynivalenol-Induced Toxicity in IPEC-J2 Cells
Toxins, 2022 Deoxynivalenol (DON), a mycotoxin that contaminates crops such as wheat and corn, can cause severe acute or chronic injury when ingested by animals or humans. This study investigated the protective effect of ferulic acid (FA), a polyphenolic substance, on alleviating the toxicity induced by DON (40 μM) in IPEC-J2 cells.
Xiangyi Meng +5 more
openaire +3 more sources
Frontiers in Immunology, 2022 Intestinal epithelial barrier injury disrupts immune homeostasis and leads to many intestinal disorders. Lactobacillus reuteri (L. reuteri) strains can influence immune system development and intestinal function.
Jingchun Gao +8 more
doaj +1 more source
, 2015 IPEC-J2 cells are intestinal porcine enterocytes isolated from the jejunum of a neonatal unsuckled piglet. The IPEC-J2 cell line is unique as it is derived from the small intestine and is neither transformed nor tumorigenic in nature. IPEC-J2 cells mimic the human physiology more closely than any other cell line of non-human origin. Therefore, it is an
openaire +1 more source
Establishment of POLDIP3 knockout IPEC-J2 cell line.
, 2023 (A) Schematic of the POLDIP3 knockout strategy. The Cas9/sgRNA target sites are indicated in red. (B and C) Confirmation of POLDIP3 knockout in IPEC-J2 cell line using DNA sequencing and Western blotting.
Jianfei Chen (3186999) +9 more
core +1 more source
Influence of high- and low-fermentable dietary fibres in sows' diet on the colostrum potential against Clostridioides difficile toxin-induced effects in IPEC-J2 cells [PDF]
, 2023 Sow colostrum has been reported to protect the IPEC-J2 cells and piglet colon tissues from detrimental effect of Clostridioides difficile toxins. Since dietary fibre can influence the colostrum composition in sows, we hypothesised that it can also ...
Grześkowiak, Łukasz M. +2 more
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IPEC-J2 cell Scanning Electron Microscope Data
, 2022 Biological Source The Porcine Intestinal Epithelial Cell line (IPEC-J2) was kindly supplied by Dr. Guoyao Wu, Faculty of Nutrition and Department of Animal Science, Texas A and M University, 2471 TAMU, College Station, USA. 1.
Shuting Cao (12640476) +7 more
core +1 more source
Pharmaceutics, 2020 The efflux pump P-glycoprotein (P-gp) affects drug distribution after absorption in humans and animals. P-gp is encoded by the multidrug resistance gene (MDR1) gene in humans, while rodents (the most common preclinical animal model) express the two ...
Lasse Saaby +4 more
doaj +1 more source
PS approximates porcine jejunal marker patterns of IPEC-J2 to that of jejunum.
, 2013 (A) Confocal immunofluorescence images of IPEC-J2/FBS, IPEC-J2/PS, and cryosectioned pig jejunal mucosae. Porcine jejunocyte marker proteins are presented in green, counterstain in red, as indicated. Nuclei are presented in blue (DAPI). In IPEC-J2, GLUT2
Juliane Rieger (485685) +10 more
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