Results 61 to 70 of about 22,373 (186)

METTL3 Regulates the Inflammatory Response in CPB2 Toxin-Exposed IPEC-J2 Cells through the TLR2/NF-κB Signaling Pathway

, 2022
Clostridium perfringens beta2 (CPB2) toxin is one of the main pathogenic toxins produced by Clostridium perfringens, which causes intestinal diseases in animals and humans.
Shuangbao Gun, Wang, Wei, Xiaoyu Huang, Jiaojiao Yang, Juanli Zhang, Xiaoli Gao, Ruirui Luo, Zhang, Juanli, Zunqiang Yan, Yang, Qiaoli, Luo, Ruirui, Zhang, Bo, Wei Wang, Gun, Shuangbao, Wang, Pengfei, Kaihui Xie, Xie, Kaihui, Jie Li, Gao, Xiaoli, Yang, Jiaojiao, Li, Jie, Bo Zhang, Huang, Xiaoyu, Qiaoli Yang, Yan, Zunqiang, Pengfei Wang   +25 more
core   +1 more source

PS does not affect junctional protein localization within cell-cell contacts but controls tight junction protein quantity of IPEC-J2.

, 2013
(A) Confocal immunofluorescence images of IPEC-J2/FBS, IPEC-J2/PS, and cryosectioned pig jejunal mucosae. Cldn5, tric, and occl are presented in green, counterstain in red, as indicated. Nuclei are presented in blue (DAPI).
Juliane Rieger (485685), Silke S. Zakrzewski (485681), In-Fah M. Lee (485684), Jan F. Richter (485682), Susanne M. Krug (181168), Jörg D. Schulzke (354049), Britta Jebautzke (485683), Monika Sachtleben (485686), Angelika Bondzio (430493), Michael Fromm (23852), Dorothee Günzel (208959)   +10 more
core   +1 more source

Comprehensive Analysis Revealed the Potential Roles of N6-Methyladenosine (m6A) Mediating E. coli F18 Susceptibility in IPEC-J2 Cells

, 2022
Post-weaning diarrhea caused by enterotoxigenic Escherichia coli F18 (E. coli F18) causes significant economic losses for pig producers. N6-methyladenosine (m6A) is a highly abundant epitranscriptomic marker that has been found to be involved in ...
Li, Tong, Bao, Wenbin, Jin, Jian, Yang, Li, Yifu Wang, Jian Jin, Zhengchang Wu, Wenbin Bao, Wu, Shenglong, Li Yang, Shenglong Wu, Tong Li, Wu, Zhengchang, Wang, Yifu   +13 more
core   +1 more source

The Inflammatory Response to Enterotoxigenic E. coli and Probiotic E. faecium in a Coculture Model of Porcine Intestinal Epithelial and Dendritic Cells

Mediators of Inflammation, 2018
The gut epithelium constitutes an interface between the intestinal contents and the underlying gut-associated lymphoid tissue (GALT) including dendritic cells (DC).
Henriette Loss, Jörg R. Aschenbach, Karsten Tedin, Friederike Ebner, Ulrike Lodemann   +4 more
doaj   +1 more source

PS reduces transepithelial, transcellular, and paracellular resistance of IPEC-J2.

, 2013
(A) Time course of transepithelial resistance (TER) of IPEC-J2, which were cultured using different culture media (FBS, fetal bovine serum; ABS, adult bovine serum; GS, adult goat serum; PS, adult porcine serum; ‘+’ indicates supplementation with ITS and
Juliane Rieger (485685), Silke S. Zakrzewski (485681), In-Fah M. Lee (485684), Jan F. Richter (485682), Susanne M. Krug (181168), Jörg D. Schulzke (354049), Britta Jebautzke (485683), Monika Sachtleben (485686), Angelika Bondzio (430493), Michael Fromm (23852), Dorothee Günzel (208959)   +10 more
core   +1 more source

Effects of different short-chain fatty acids (SCFA) on gene expression of proteins involved in barrier function in IPEC-J2 [PDF]

, 2022
BACKGROUND: Gut microbial anaerobic fermentation produces short-chain fatty acids (SCFA), which are important substrates for energy metabolism and anabolic processes in mammals.
Ferrari, Luca, Martelli, Paolo, Borghetti, Paolo, Andrani, Melania, Cavalli, Valeria, Saleri, Roberta, De Angelis, Elena, Ravanetti, Francesca, Paolo Borghetti, Luca Ferrari, Roberta Saleri, Melania Andrani, Paolo Martelli, Francesca Ravanetti, Elena De Angelis, Valeria Cavalli   +15 more
core   +1 more source

Lactobacillus salivarius alleviates inflammation via NF-κB signaling in ETEC K88-induced IPEC-J2 cells

Journal of Animal Science and Biotechnology, 2020
Background Enterotoxigenic Escherichia coli (ETEC) K88 commonly colonize in the small intestine and keep releasing enterotoxins to impair the intestinal barrier function and trigger inflammatory reaction. Although Lactobacillus salivarius (L. salivarius)
Jiayun Qiao, Zeyang Sun, Dongmei Liang, Haihua Li   +3 more
doaj   +1 more source

PS elevates active ion transport and membrane capacitance of IPEC-J2.

, 2013
(A) Forskolin-induced short-circuit current (▵ISC) of IPEC-J2/FBS (white bar) and IPEC-J2/PS (light grey bar) were corrected for surface enlargement by villi and crypts of porcine jejunum (factor 10) (▵ISCcorr) for comparison with pig jejunal values ...
Juliane Rieger (485685), Silke S. Zakrzewski (485681), In-Fah M. Lee (485684), Jan F. Richter (485682), Susanne M. Krug (181168), Jörg D. Schulzke (354049), Britta Jebautzke (485683), Monika Sachtleben (485686), Angelika Bondzio (430493), Michael Fromm (23852), Dorothee Günzel (208959)   +10 more
core   +1 more source

Deoxynivalenol triggers porcine intestinal tight junction disorder: Insights from mitochondrial dynamics and mitophagy

Ecotoxicology and Environmental Safety, 2022
Deoxynivalenol (DON) is universally detected trichothecene in most cereal commodities, which is considered as a major hazardous material for human and animal health.
Cong Zhang, Ke-Fei Zhang, Feng-Juan Chen, Yun-He Chen, Xu Yang, Zi-Hui Cai, Yi-Bao Jiang, Xue-Bing Wang, Gai-Ping Zhang, Fang-Yu Wang   +9 more
doaj   +1 more source

PS approximates tight junction ultrastructure of IPEC-J2 to pig jejunum.

, 2013
(A) Freeze-fracture images of IPEC-J2/FBS, IPEC-J2/PS, and pig jejunal tissue (scale bar: 200 nm). (B) Morphometric analysis of the TJ meshwork depth, (C) the number of horizontal strands, and (D) the TJ strand type (continuous vs. particle type).
Juliane Rieger (485685), Silke S. Zakrzewski (485681), In-Fah M. Lee (485684), Jan F. Richter (485682), Susanne M. Krug (181168), Jörg D. Schulzke (354049), Britta Jebautzke (485683), Monika Sachtleben (485686), Angelika Bondzio (430493), Michael Fromm (23852), Dorothee Günzel (208959)   +10 more
core   +1 more source