Results 11 to 20 of about 22,373 (186)

Improved cell line IPEC-J2, characterized as a model for porcine jejunal epithelium. [PDF]

open access: yesPLoS ONE, 2013
Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular level and furthermore help to reduce animal usage.
Silke S Zakrzewski   +10 more
doaj   +6 more sources

The function of antimicrobial peptide MPX on the apoptosis and barrier of IPEC-J2 cells [PDF]

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2021
The porcine intestinal epithelial cell line IPEC-J2 cells, which were isolated from neonatal piglet mid-jejunum, the main components of the intestinal epithelium and play an important role in the intestine.
Xueqin Zhao
doaj   +3 more sources

TGF-β from the Porcine Intestinal Cell Line IPEC-J2 Induced by Porcine Circovirus 2 Increases the Frequency of Treg Cells via the Activation of ERK (in CD4+ T Cells) and NF-κB (in IPEC-J2)

open access: yesViruses, 2022
Porcine circovirus 2 (PCV2) causes immunosuppression. Piglets infected with PCV2 can develop enteritis. Given that the gut is the largest immune organ, however, the response of the gut’s immune system to PCV2 is still unclear.
Xuewei Liu   +7 more
doaj   +2 more sources

Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 cells [PDF]

open access: yesPeerJ, 2023
Background S100 calcium-binding protein A9 (S100A9) is a commonly known pro-inflammatory factor involved in various inflammatory responses. Clostridium perfringens (C. perfringens ) type C is known to cause diarrhea in piglets.
Jie Li   +6 more
doaj   +3 more sources

Comparison of expression profiles between undifferentiated and differentiated porcine IPEC-J2 cells [PDF]

open access: yesPorcine Health Management, 2022
Background The intestinal porcine enterocyte cell line (IPEC-J2) is a well-established model to study porcine intestinal physiology. IPEC-J2 cells undergo spontaneous differentiation during culture while changes in expression patterns of differentiated ...
Guolin Pi   +4 more
doaj   +3 more sources

Integrins Were Involved in Soybean Agglutinin Induced Cell Apoptosis in IPEC-J2 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Abstract: Soybean agglutinin (SBA), is a non-fiber carbohydrate related protein and a major anti-nutritional factor. Integrins, transmembrane glycoproteins, are involved in many biological processes. Although recent work suggested that integrins are involved in SBA-induced cell-cycle alterations, no comprehensive study has reported whether integrins ...
Li Pan   +5 more
openaire   +3 more sources

Low-Molecular-Weight Chitosan Attenuates Lipopolysaccharide-Induced Inflammation in IPEC-J2 Cells by Inhibiting the Nuclear Factor-κB Signalling Pathway

open access: yesMolecules, 2021
Low-molecular-weight chitosan (LMWC), a product of chitosan deacetylation, possesses anti-inflammatory effects. In the present study, a porcine small intestinal epithelial cell line, IPEC-J2, was used to assess the protective effects of LMWC on ...
Jiao Zhang   +4 more
doaj   +2 more sources

Protective Effects of L-Theanine on IPEC-J2 Cells Growth Inhibition Induced by Dextran Sulfate Sodium via p53 Signaling Pathway

open access: yesMolecules, 2021
L-theanine is a nonprotein amino acid found in tea leaves and has been widely used as a safe food additive in beverages or foods because of its varied bioactivities.
Longlin Zhang   +5 more
doaj   +2 more sources

Comparing Two Intestinal Porcine Epithelial Cell Lines (IPECs): Morphological Differentiation, Function and Metabolism. [PDF]

open access: yesPLoS ONE, 2015
The pig shows genetical and physiological resemblance to human, which predestines it as an experimental animal model especially for mucosal physiology. Therefore, the intestinal epithelial cell lines 1 and J2 (IPEC-1, IPEC-J2)--spontaneously immortalised
Constanze Nossol   +9 more
doaj   +1 more source

Lycopene Maintains Mitochondrial Homeostasis to Counteract the Enterotoxicity of Deoxynivalenol

open access: yesAntioxidants, 2023
The intestinal tract is a target organ for Deoxynivalenol (DON) absorption and toxicity. Mitochondrial homeostasis imbalance is the gut toxicity mechanism of DON. Lycopene (LYC) has intestinal protective effects and can maintain mitochondrial homeostasis
Zihui Cai   +5 more
doaj   +1 more source

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