Comparison of expression profiles between undifferentiated and differentiated porcine IPEC-J2 cells [PDF]
Porcine Health Management, 2022 Background The intestinal porcine enterocyte cell line (IPEC-J2) is a well-established model to study porcine intestinal physiology. IPEC-J2 cells undergo spontaneous differentiation during culture while changes in expression patterns of differentiated ...
Guolin Pi +4 more
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Improved cell line IPEC-J2, characterized as a model for porcine jejunal epithelium. [PDF]
PLoS ONE, 2013 Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular level and furthermore help to reduce animal usage.
Silke S Zakrzewski +10 more
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Silver and Copper Nanoparticles Hosted by Carboxymethyl Cellulose Reduce the Infective Effects of Enterotoxigenic Escherichia coli:F4 on Porcine Intestinal Enterocyte IPEC-J2 [PDF]
MicroorganismsZero-valent copper and silver metals (Ms) nanoparticles (NPs) supported on carboxymethylcellulose (CMC) were synthesized for treating Enterotoxigenic Escherichia coli fimbriae 4 (ETEC:F4), a major cause of diarrhea in post-weaned pigs.
Armelle Tchoumi Neree +6 more
doaj +2 more sources
Toxins, 2019 The presence of tannic acid (TA), which is widely distributed in plants, limits the utilization of non-grain feed. Illustrating the toxicity mechanism of TA in animals is important for preventing poisoning and for clinical development of TA.
Ji Wang +6 more
doaj +3 more sources
Genistein Alleviates Intestinal Oxidative Stress by Activating the Nrf2 Signaling Pathway in IPEC-J2 Cells [PDF]
Veterinary SciencesIn the weaning period, piglets often face oxidative stress, which will cause increased diarrhea and mortality. Genistein, a flavonoid, which is extracted from leguminous plants, possesses anti-inflammatory and antioxidative bioactivities. However, little
Yanpin Li +6 more
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Carvacrol Protects IPEC-J2 Cells from Oxidative Stress by Suppressing Autophagy. [PDF]
Int J Mol SciOxidative stress impairs intestinal function and causes poor growth performance in piglets. Carvacrol is a natural essential oil, and its anti-oxidative and anti-inflammatory activities in the intestines of piglets have been reported in many studies.
Hsu MC, Wang HT, Chen CY.
europepmc +3 more sources
Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 cells [PDF]
PeerJ, 2023 Background S100 calcium-binding protein A9 (S100A9) is a commonly known pro-inflammatory factor involved in various inflammatory responses. Clostridium perfringens (C. perfringens ) type C is known to cause diarrhea in piglets.
Jie Li +6 more
doaj +2 more sources
Vitamin K Vitamers Differently Affect Energy Metabolism in IPEC-J2 Cells [PDF]
Frontiers in Molecular Biosciences, 2021 The fat-soluble vitamin K (VK) has long been known as a requirement for blood coagulation, but like other vitamins, has been recently recognized to play further physiological roles, particularly in cell development and homeostasis. Vertebrates cannot de novo synthesize VK, which is essential, and it can only be obtained from the diet or by the activity
Chiara Bernardini +7 more
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Trolox and ascorbic acid reduce direct and indirect oxidative stress in the IPEC-J2 cells, an in vitro model for the porcine gastrointestinal tract [PDF]
, 2015 Oxidative stress in the small intestinal epithelium is a major cause of barrier malfunction and failure to regenerate. This study presents a functional in vitro model using the porcine small intestinal epithelial cell line IPEC-J2 to examine the effects ...
De Smet, Stefaan +7 more
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SLC4A11 and MFSD3 Gene Expression Changes in Deoxynivalenol Treated IPEC-J2 Cells [PDF]
Frontiers in Genetics, 2021 Deoxynivalenol (DON) caused serious cytotoxicity for animal cells. However, genes involved in regulating DON toxicity and the underlying molecular mechanisms remain largely unknown. This study explored the role of SLC4A11 and MFSD3 in alleviating DON toxicity and analyzed the DNA methylation changes of these two genes. Viability and cell cycle analysis
Yafei Xu +9 more
openaire +3 more sources