Results 21 to 30 of about 4,777,996 (166)
In vitro characterization of TMPRSS2 inhibition in IPEC-J2 cells [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 The transmembrane serine protease, TMPRSS2 is an important target in the treatment of seasonal influenza infections and contributes to prostate carcinogenesis and metastasis. In this study, the effect of the synthetic TMPRSS2 inhibitor I-432 on jejunal IPEC-J2 cell monolayers cultured on membrane inserts was characterized. Using a fluorogenic substrate,
Pászti-Gere, Erzsébet +5 more
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SLC4A11 and MFSD3 Gene Expression Changes in Deoxynivalenol Treated IPEC-J2 Cells [PDF]
Frontiers in Genetics, 2021 Deoxynivalenol (DON) caused serious cytotoxicity for animal cells. However, genes involved in regulating DON toxicity and the underlying molecular mechanisms remain largely unknown. This study explored the role of SLC4A11 and MFSD3 in alleviating DON toxicity and analyzed the DNA methylation changes of these two genes. Viability and cell cycle analysis
Yafei Xu +9 more
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Effects of Different Methionine Sources on Methionine Metabolism in the IPEC-J2 Cells [PDF]
BioMed Research International, 2019 As one of the essential amino acids, methionine (Met) plays an important role in biological events such as methylation and antioxidant properties besides its function in protein synthesis. Different Met sources have been used in animal production, but their effects on Met metabolic pathways are not well understood. In the present study, we investigated
Fangrui Zuo +4 more
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Vitamin K Vitamers Differently Affect Energy Metabolism in IPEC-J2 Cells [PDF]
Frontiers in Molecular Biosciences, 2021 The fat-soluble vitamin K (VK) has long been known as a requirement for blood coagulation, but like other vitamins, has been recently recognized to play further physiological roles, particularly in cell development and homeostasis. Vertebrates cannot de novo synthesize VK, which is essential, and it can only be obtained from the diet or by the activity
Chiara Bernardini +7 more
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Antioxidants, 2022 Transmissible gastroenteritis virus (TGEV) can cause diarrhea, dehydration, and high mortality in piglets, which is closely related to intestinal epithelial cell apoptosis caused by TGEV infection.
Junning Pu +11 more
doaj +1 more source
Profiling of alternative polyadenylation and gene expression in PEDV-infected IPEC-J2 cells [PDF]
Virus Genes, 2021 Since 2010, porcine epidemic diarrhea virus (PEDV) has received global attention with the emergence of variant strains characterized with high pathogenicity. The pathogen-host interaction after PEDV infection is still unclear. To investigate this issue, high-throughput-based sequencing technology is one of the optimal choices. In this study, we used in
Xiaona Wei +5 more
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Microorganisms, 2021 The neonatal Fc receptor (FcRn) transports maternal immunoglobulin G (IgG) to the foetus or newborn and protects the IgG from degradation. FcRn is expressed in several porcine tissues and cell types and its expression levels are regulated by immune and ...
Shaoju Qian +5 more
doaj +1 more source
IPEC-J2 cell Scanning Electron Microscope Data
, 2022 Biological Source The Porcine Intestinal Epithelial Cell line (IPEC-J2) was kindly supplied by Dr. Guoyao Wu, Faculty of Nutrition and Department of Animal Science, Texas A and M University, 2471 TAMU, College Station, USA. 1.
Shuting Cao (12640476) +7 more
core +1 more source
Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments [PDF]
Virology Journal, 2014 Porcine circovirus-associated disease (PCVAD) is caused by a small pathogenic DNA virus, Porcine circovirus type 2 (PCV2), and is responsible for severe economic losses. PCV2-associated enteritis appears to be a distinct clinical manifestation of PCV2.
Yan, Mengfei, Zhu, Liqi, Yang, Qian
openaire +2 more sources
, 2022 Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 ...
Jie Li (13877648)
core +1 more source