Results 11 to 20 of about 5,753 (209)

Comparison of expression profiles between undifferentiated and differentiated porcine IPEC-J2 cells [PDF]

Porcine Health Management, 2022
Background The intestinal porcine enterocyte cell line (IPEC-J2) is a well-established model to study porcine intestinal physiology. IPEC-J2 cells undergo spontaneous differentiation during culture while changes in expression patterns of differentiated ...
Guolin Pi, Wenxin Song, Zijuan Wu, Yali Li, Huansheng Yang   +4 more
doaj   +3 more sources

Porcine IPEC-J2 intestinal epithelial cells in microbiological investigations [PDF]

Veterinary Microbiology, 2012
IPEC-J2 cells are porcine intestinal columnar epithelial cells that were isolated from neonatal piglet mid-jejunum. This cell line forms polarized monolayers with high transepithelial electrical resistance when cultured on 0.4 μm pore-size filters. The cell line is unique in that it is derived from small intestinal tissue (compared to the common human ...
Amanda J, Brosnahan, David R, Brown
openaire   +4 more sources

Improved cell line IPEC-J2, characterized as a model for porcine jejunal epithelium. [PDF]

PLoS ONE, 2013
Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular level and furthermore help to reduce animal usage.
Silke S Zakrzewski, Jan F Richter, Susanne M Krug, Britta Jebautzke, In-Fah M Lee, Juliane Rieger, Monika Sachtleben, Angelika Bondzio, Jörg D Schulzke, Michael Fromm, Dorothee Günzel   +10 more
doaj   +4 more sources

Exogenous Glutathione Protects IPEC-J2 Cells against Oxidative Stress through a Mitochondrial Mechanism

Molecules, 2022
The accumulation of reactive oxygen species (ROS) triggers oxidative stress in cells by oxidizing and modifying various cellular components, preventing them from performing their inherent functions, ultimately leading to apoptosis and autophagy. Glutathione (GSH) is a ubiquitous intracellular peptide with multiple functions.
Qiuyu Chen, Miao Yu, Zhimei Tian, Yiyan Cui, Dun Deng, Ting Rong, Zhichang Liu, Min Song, Zhenming Li, Xianyong Ma, Huijie Lu   +10 more
openaire   +5 more sources

Carvacrol Protects IPEC-J2 Cells from Oxidative Stress by Suppressing Autophagy. [PDF]

Int J Mol Sci
Oxidative stress impairs intestinal function and causes poor growth performance in piglets. Carvacrol is a natural essential oil, and its anti-oxidative and anti-inflammatory activities in the intestines of piglets have been reported in many studies.
Hsu MC, Wang HT, Chen CY.
europepmc   +3 more sources

Persistence Infection of TGEV Promotes Enterococcus faecalis Infection on IPEC-J2 Cells. [PDF]

Int J Mol Sci, 2022
Transmissible gastroenteritis virus (TGEV) is a coronavirus causing diarrhea with high incidence in swine herds. Its persistent infection might lead to epithelial-mesenchymal transition (EMT) of swine intestinal epithelial cells, followed by subsequent infections of other pathogens. Enterococcus faecalis (E.
Guo Z, Zhang C, Dong J, Wang Y, Hu H, Chen L.   +5 more
europepmc   +3 more sources

Vitamin K Vitamers Differently Affect Energy Metabolism in IPEC-J2 Cells [PDF]

Frontiers in Molecular Biosciences, 2021
The fat-soluble vitamin K (VK) has long been known as a requirement for blood coagulation, but like other vitamins, has been recently recognized to play further physiological roles, particularly in cell development and homeostasis. Vertebrates cannot de novo synthesize VK, which is essential, and it can only be obtained from the diet or by the activity
Chiara Bernardini, Cristina Algieri, Debora La Mantia, Fabiana Trombetti, Alessandra Pagliarani, Monica Forni, Monica Forni, Salvatore Nesci   +7 more
openaire   +4 more sources

<i>Parabacteroides goldsteinii</i> mitigates the lipopolysaccharide-induced inflammatory response in IPEC-J2 cells. [PDF]

Front Vet Sci
IntroductionThe misuse of antibiotics threatens animal health and food safety and limits the development of livestock and poultry farming. In animal husbandry, probiotics can be used as an alternative to antibiotics because of their environmental protection and high efficiency.
Zhang J, Li A, He Y, Guo T, Ge Y, Pan H, Dong C.   +6 more
europepmc   +4 more sources

SLC4A11 and MFSD3 Gene Expression Changes in Deoxynivalenol Treated IPEC-J2 Cells [PDF]

Frontiers in Genetics, 2021
Deoxynivalenol (DON) caused serious cytotoxicity for animal cells. However, genes involved in regulating DON toxicity and the underlying molecular mechanisms remain largely unknown. This study explored the role of SLC4A11 and MFSD3 in alleviating DON toxicity and analyzed the DNA methylation changes of these two genes. Viability and cell cycle analysis
Yafei Xu, Xiaolei Chen, Luchen Yu, Yi Wang, Haifei Wang, Zhengchang Wu, Shenglong Wu, Shenglong Wu, Wenbin Bao, Wenbin Bao   +9 more
openaire   +3 more sources

Effects of daidzein on antioxidant capacity in weaned pigs and IPEC-J2 cells. [PDF]

Anim Nutr, 2022
Our previous study found that soybean isoflavones in soybean meal play an important role in improving growth performance and antioxidant capacity in pigs. However, it is still unknown whether long-term supplementation with daidzein, an active molecule deglycosylated from daidzin, in a corn-soybean meal diet can enhance growth performance in pigs. Thus,
Li Y, Jiang X, Cai L, Zhang Y, Ding H, Yin J, Li X.   +6 more
europepmc   +4 more sources