Results 31 to 40 of about 4,777,996 (166)
Protective Effects of Ferulic Acid on Deoxynivalenol-Induced Toxicity in IPEC-J2 Cells
Toxins, 2022 Deoxynivalenol (DON), a mycotoxin that contaminates crops such as wheat and corn, can cause severe acute or chronic injury when ingested by animals or humans. This study investigated the protective effect of ferulic acid (FA), a polyphenolic substance, on alleviating the toxicity induced by DON (40 μM) in IPEC-J2 cells.
Xiangyi Meng +5 more
openaire +3 more sources
STIM1 promotes IPEC-J2 porcine epithelial cell restitution by TRPC1 signaling
Animal Biotechnology, 2021 Intestinal epithelial restitution is partly dependent on cell migration, which reseals superficial wounding after injury. Here, we tested the hypothesis that stromal interaction molecule 1(STIM1) regulates porcine intestinal epithelial cell migration by activating transient receptor potential canonical 1 (TRPC1) signaling.
Weiwei Mo +6 more
openaire +2 more sources
BMC Veterinary Research, 2022 Background Antimicrobial peptides including various defensins have been attracting considerable research interest worldwide, as they have potential to substitute for antibiotics. Moreover, AMPs also have immunomodulatory activity.
Qingqing Fu +11 more
doaj +1 more source
FTO Regulates Apoptosis in CPB2-Treated IPEC-J2 Cells by Targeting Caspase 3 Apoptotic Protein
, 2022 SIMPLE SUMMARY: Fat mass and obesity associated protein (FTO) is a key demethylase in the process of bacterial diarrhea in piglets. However, the involvement of FTO in infectious diarrhea caused by Clostridium perfringens type C is not known.
Shuangbao Gun +23 more
core +1 more source
Gallic acid mitigates LPS‐induced inflammatory response via suppressing NF‐κB signalling pathway in IPEC‐J2 cells [PDF]
, 2022 peer reviewedGallic acid is a phenolic compound that exhibits antibacterial, antioxidative and anti-inflammatory functions. In a previous study, we found that dietary supplementation with gallic acid decreased incidence of diarrhoea and protected ...
Li, Xilong +11 more
core +1 more source
Penetration of Fosfomycin into IPEC-J2 Cells in the Presence or Absence of Deoxynivalenol
PLoS ONE, 2013 La fosfomycine (Fos) est un antibiotique utilisé dans les élevages porcins pour le traitement et la prévention des infections causées par des bactéries résistantes après le sevrage. Des antibiotiques et des concentrations non toxiques de mycotoxines, telles que le déoxynivalénol (DON), sont fréquemment présents dans l'alimentation des animaux.
Guadalupe Martínez +3 more
openaire +5 more sources
Cells, 2023 Piglet diarrhea caused by Clostridium perfringens (C. perfringens) type C (CpC) seriously endangers the development of the pig production industry. C. perfringens beta2 (CPB2) toxin is a virulent toxin produced by CpC.
Kaihui Xie +7 more
doaj +1 more source
Frontiers in Immunology, 2022 Transmissible gastroenteritis virus (TGEV) infection can cause transmissible gastroenteritis (TGE), especially in suckling piglets, resulting in a significant economic loss for the global pig industry.
Junning Pu +11 more
doaj +1 more source
, 2021 Clostridium perfringens (C. perfringens) causes intestinal injury through overgrowth and the secretion of multiple toxins, leading to diarrhea and necrotic enteritis in animals, including pigs, chickens, and sheep.
Zihan Zeng +8 more
core +1 more source
JNK molecule is a toxic target for IPEC-J2 cell barrier damage induced by T-2 toxin
Ecotoxicology and Environmental Safety, 2023 The most prevalent contaminated mycotoxin in feed and grain is T-2 toxin. The T-2 toxin's primary action target is the gut because it is the main organ of absorption.
Fengjuan Chen +6 more
doaj +1 more source