Results 61 to 70 of about 4,777,996 (166)
Weanling stress and toxicosis, which are harmful to the health of pigs’ intestines, are associated with oxidative stress. Quercetin (Que) is a polyphenolic compound that shows good anti-cancer, anti-inflammation and anti-oxidation effects.
Zhigang Chen +5 more
doaj +1 more source
OTE attenuated the dextran sulfate sodium (DSS)–induced colitis by preserving intestinal barrier integrity, reducing oxidative stress and regulating inflammatory cytokines associated with gut microbiota–SCFAs–IL‐22 axis. ABSTRACT This study was conducted to investigate the protective effect of oolong tea extracts (OTEs) on colitis and explore its ...
Wenwen Fang +9 more
wiley +1 more source
Polarisation of IPEC-1 and IPEC-J2, confocal microscopy and transmission electron microscopy.
(A) Ten days old IPEC-1 and IPEC-J2 cells were fixed and stained for ZO-1 (Zonula occludens, green) and beta-catenin (Zonula adherens, red). Both cells lines showed a polarised structure with ZO-1 immunoreactivity at the apical pole and the underlying ...
Constanze Nossol (326870) +9 more
core +1 more source
Effects of 1,2-Dimethylhydrazine on Barrier Properties of Rat Large Intestine and IPEC-J2 Cells [PDF]
Colon cancer is accompanied by a decrease of epithelial barrier properties, which are determined by tight junction (TJ) proteins between adjacent epithelial cells.
Alexander G. Markov +7 more
core +1 more source
Intestinal epithelial barrier injury disrupts immune homeostasis and leads to many intestinal disorders. Lactobacillus reuteri (L. reuteri) strains can influence immune system development and intestinal function.
Jingchun Gao +8 more
doaj +1 more source
Rooibos (Aspalathus linearis) is rich in bioactive polyphenols, but extraction and processing methods can substantially influence its composition and biological activity. This study investigated enriched ethanolic extracts from unfermented and fermented rooibos in an LPS‐stimulated IPEC‐J2 intestinal epithelial cell model. Despite marked differences in
Shana De Bruyn‐Orr +4 more
wiley +1 more source
Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du +10 more
wiley +1 more source
Inhibition of Salmonella Binding to Porcine Intestinal Cells by a Wood-Derived Prebiotic
Numerous Salmonella enterica serovars can cause disease and contamination of animal-produced foods. Oligosaccharide-rich products capable of blocking pathogen adherence to intestinal mucosa are attractive alternatives to antibiotics as these have ...
Aleksandar Božić +10 more
doaj +1 more source
Extracellular vesicles (EVs) derived from C. butyricum can enter intestinal epithelial cells and mediate the anti‐lipid absorption effects by delivering miRNA‐like RNAs (milRNAs), particularly milRNA‐3020179, which primarily targeted host genes majorly including PPARα. Deletion of milRNA‐3020179 in C. butyricum abolished its effects on lipid deposition
Hong Hu +9 more
wiley +1 more source
PS approximates porcine jejunal marker patterns of IPEC-J2 to that of jejunum.
(A) Confocal immunofluorescence images of IPEC-J2/FBS, IPEC-J2/PS, and cryosectioned pig jejunal mucosae. Porcine jejunocyte marker proteins are presented in green, counterstain in red, as indicated. Nuclei are presented in blue (DAPI). In IPEC-J2, GLUT2
Juliane Rieger (485685) +10 more
core +1 more source

