Results 81 to 90 of about 4,777,996 (166)

Potassium Diformate Attenuates Inflammation and Enhances Intestinal Barrier Function Associated With Gut Microbiota Modulation in Nursery Piglets

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Twenty‐four weaned piglets were assigned to four dietary groups supplemented with 0%, 0.6%, 1.2%, or 1.8% K‐diformate for 28 days. Dietary addition with K‐diformate (especially 1.8%) improved growth performance, inflammation, and intestinal barrier function associated with gut microbiota modulation in nursery piglets.
Tiande Zou, Lina Zhang, Qin Li, Yong Cheng, Li Lu, Songtao Zhong, Mingren Qu, Jun Chen   +7 more
wiley   +1 more source

Image_1_Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus.TIF

, 2022
Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Yawen Wang (1578763), Tanqing Li (8872859), Qinye Song (14097276), Haiyong Guo (8872856), Zuojun Yao (14097273), Lidan Sun (391982), Ligong Chen (259976), Chen Yuan (3383267), Limin Li (126729)   +8 more
core   +1 more source

Engineered Bacillus subtilis regulates intestinal barrier in ETEC K88‐infected piglets and modulates miR‐1250‐5p/NFκB pathway in IPEC‐J2

iMetaOmics, Volume 3, Issue 2, June 2026.
Upon enterotoxigenic Escherichia coli (ETEC) K88 infection, intestinal barrier function is disrupted with compromised tight junctions, accompanied by an exacerbated inflammatory response, proliferation of pathogenic Escherichia, and depletion of beneficial Lactobacillus paralimentarius.
Chaoyue Wen, Hong Zhang, Qiuping Guo, Yehui Duan, Sisi Chen, Mengmeng Han, Leli Wang, Le Huang, Yuankun Deng, Fengna Li, Yizhen Wang, Mingliang Jin   +11 more
wiley   +1 more source

The Integrins Involved in Soybean Agglutinin-Induced Cell Cycle Alterations in IPEC-J2

Molecules and Cells, 2017
Soybean agglutinin (SBA) is an anti-nutritional factor of soybean, affecting cell proliferation and inducing cytotoxicity. Integrins are transmembrane receptors, mediating a variety of cell biological processes. This research aims to study the effects of SBA on cell proliferation and cell cycle progression of the intestinal epithelial cell line from ...
Pan, Li, Zhao, Yuan, Yuan, Zhijie, Farouk, Mohammed Hamdy, Zhang, Shiyao, Bao, Nan, Qin, Guixin   +6 more
openaire   +3 more sources

Spirobenzofuran Mitigates Ochratoxin A-Mediated Intestinal Adverse Effects in Pigs through Regulation of Beta Defensin 1

Toxics
Antimicrobial peptides (AMPs) function to extensively suppress various problematic factors and are considered a new alternative for improving livestock health and enhancing immunomodulation.
Jung Woong Yoon, Myoung Ok Kim, Sangsu Shin, Woo-Sung Kwon, Soo Hyun Kim, Yun-Ju Kwon, Sang In Lee   +6 more
doaj   +1 more source

Culture Optimization of the IPEC–J2 Piglet Jejunum Cell Line for Applications in Infant Nutrition Research

Molecular Nutrition &Food Research, Volume 70, Issue 12, 28 June 2026.
IPEC–J2 cell line is derived from piglet jejunal cells. Four different culture media were assessed for their ability to support IPEC‐J2 differentiation into an in vitro gut barrier. PS10 media proved most successful. Once differentiated with PS10, the IPEC‐J2 barrier was sufficiently robust for treatment with digested infant food. This demonstrates the
Francesca Bietto, Myriam M.‐L. Grundy, Elena Arranz, Sandra Wiart‐Letort, Eva Rath, Alice J. Lucey, Linda Giblin   +6 more
wiley   +1 more source

IPEC-J2 as a cellular model for studying intestinal mucus

Scientific Reports
Mucus in the proximal small intestine serves critical protective and transport functions, regulating nutrient absorption to enterocytes. The porcine jejunal epithelial cell line IPEC-J2 is widely used to study epithelial barrier function, yet its ...
Frédéric Dessauge, Annie Vincent, Christine Trefeu, Frédérique Mayeur-Nickel, Sandra Wiart-Letort, Adam Macierzanka, Martin Beaumont, Myriam M.-L. Grundy   +7 more
doaj   +1 more source

Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation

Frontiers in Nutrition
BackgroundLuteolin (LUT), a flavonoid compound widely present in natural plants, has been extensively studied for its diverse biological properties, involving anti-inflammatory,antioxidant, anti-apoptosis and other properties.MethodsThe aim of this study
Jianyun Yuan, Ke Zhang, Lingling Yang, Xinyi Cheng, Jinyan Chen, Xiaoquan Guo, Huabin Cao, Caiying Zhang, Chenghong Xing, Guoliang Hu, Yu Zhuang   +10 more
doaj   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

Effect of glucose in the IPEC-J2 cell culture media on adherence of porcine ETEC strains to porcine epithelial (IPEC-J2) cells.

, 2014
IPEC-J2 cells in the presence of DMEM-F12 media containing 0, 0.25, 0.5, 1 and 2% glucose were inoculated with a 2 h culture of strain WAM2137 (spontaneous nalidixic acid-resistant mutant derivative of wild-type LT+ STb +2534-86), MUN300 [LT− STb ...
Prageeth Wijemanne (663422), Rodney A. Moxley (663423)   +1 more
core   +1 more source