Results 101 to 110 of about 5,753 (209)

Applying the adverse outcome pathway (AOP) for food sensitization to support in vitro testing strategies [PDF]

, 2019
Background Before introducing proteins from new or alternative dietary sources into the market, a compressive risk assessment including food allergic sensitization should be carried out in order to ensure their safety.
Benedé, Sara, Bouchaud, Grégory, Costa, Ana, Denery-Papini, Sandra, Díaz-Perales, Araceli, E.M. Willemsen, Linette, Garrido-Arandia, María, Gavrovic-Jankulovic, Marija, H.M. van Bilsen, Jolanda, Hayen, Simone, L. Bavaro, Simona, L. Roggen, Erwin, Lozano-Ojalvo, Daniel, M. Antunes, Célia, Wróblewska, Mónica   +14 more
core   +1 more source

Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol‐Lowering Compound Library

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Yaqin Li, Panpan Qin, Kaiqi Zhang, Ningning Ma, Tianliang Wang, Zilu Chen, Yixin Yuan, Dongliang Li, Linyang Yu, Wentao Li, Wenjuan Du, Yongtao Li, Jianchao Wei   +12 more
wiley   +1 more source

Glycinin-induced porcine IPEC-J2 cell damage via the NF-κB/MAPK signaling pathway [PDF]

, 2020
Abstract Background: Glycinin, a protein found in soybean, is a human and animal allergen. It been previously shown to damage the intestinal barrier. However, its mechanisms of action remain unclear. Therefore, in this study, the intestinal porcine epithelial cell line IPEC-J2 was used to study the effect of glycinin concentration on the ...
Chenglu Peng, Zhifeng Sun, Lei Wang, Yingshuang Shu, Mengchu He, Hongyan Ding, Yu Li, Xichun Wang, Shibin Feng, Jinchun Li, Jinjie Wu   +10 more
openaire   +2 more sources

Interactions between dietary chicory, gut microbiota and immune responses [PDF]

, 2013
This thesis provides a better understanding of interactions between diet, gut microbiota, and immune responses to a specific dietary fiber source, chicory (Cichorium intybus L).
Liu, Haoyu
core  

Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang, Yuqian Liu, Shuying Ren, Zhouyuan Wang, Yunxia Li, Lianci Peng, Rendong Fang, Jianchao Wei   +7 more
wiley   +1 more source

IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross‐Species Conservation

Advanced Science, Volume 12, Issue 47, December 18, 2025.
A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu, Qinqin Xie, Xiaodian Cai, Zhanming Zhong, Ran Wei, He Han, Shuang Liu, Zhenyang Zhang, Lingyao Xu, Zitao Chen, Zhe Zhang, Qishan Wang, Yuchun Pan, Zhen Wang, Zhe Zhang   +14 more
wiley   +1 more source

Lack of LTβR Increases Susceptibility of IPEC-J2 Cells to Porcine Epidemic Diarrhea Virus [PDF]

Cells, 2018
The essential requirement of the lymphotoxin beta receptor (LTβR) in the development and maintenance of peripheral lymphoid organs is well recognized. Evidence shows that LTβR is involved in various cellular processes; however, whether it plays a role in maintaining the cellular function of intestinal porcine enterocytes (IPEC-J2), specifically during ...
Altawaty, Tawfeek, Liu, Lulu, Zhang, Hongyong, Tao, Cong, Hou, Shaohua, Li, Kui, Wang, Yanfang   +6 more
openaire   +3 more sources

IPEC-J2 as a cellular model for studying intestinal mucus

Scientific Reports
Mucus in the proximal small intestine serves critical protective and transport functions, regulating nutrient absorption to enterocytes. The porcine jejunal epithelial cell line IPEC-J2 is widely used to study epithelial barrier function, yet its ...
Frédéric Dessauge, Annie Vincent, Christine Trefeu, Frédérique Mayeur-Nickel, Sandra Wiart-Letort, Adam Macierzanka, Martin Beaumont, Myriam M.-L. Grundy   +7 more
doaj   +1 more source

A bélhámsejtek oxidatív stressz okozta gyulladásának gátlása probiotikus tejsavbaktériumokkal: hatásmechanizmus és alkalmazhatóság antibiotikum-helyettesítő hozamfokozásra választási malacokon = Attenuation of oxidative stress-induced inflammation by probiotic lactobacilli in intestinal epithelial cells: mechanism of action and application as antibiotic-substitute in weanling pigs [PDF]

, 2012
Az akut oxidatív stressz és a probiotikumok hatásának vizsgálatához kollagénnel bevont poliészter membrán inzerten tenyésztett, újszülött sertés jejunum eredetű IPEC-J2 sejtvonalat alkalmaztunk.
Csikó, György, Csizinszky, Rita, Gálfi, Péter, Jerzsele, Ákos, Kővágó, Csaba, Lehel, József, Nagy, Gábor, Szekér, Krisztina   +7 more
core  

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

Advanced Science, Volume 12, Issue 45, December 4, 2025.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan, Yinfeng Lyu, Yi Liu, Jianping Ren, Yue Zhao, Licong Zhang, Anshan Shan   +6 more
wiley   +1 more source