Results 121 to 130 of about 4,777,996 (166)

Modelling ferroptosis in IPEC-J2 cells: insights into iron-dependent cell death

Italian Journal of Animal Science
Ferroptosis, a form of regulated cell death characterised by iron accumulation and lipid peroxidation, plays a crucial role in various diseases. However, its mechanisms in livestock, particularly in pigs, remain unclear. In this study, we established an in vitro ferroptosis model using the porcine intestinal epithelial cell line IPEC-J2 to investigate ...
Ching-Hsuan Liu, Yuan-Yu Lin
openaire   +2 more sources

PS affects permeability to fluorescein but not charge selectivity of IPEC-J2.

, 2013
(A) Paracellular permeability to fluorescein (PFLU) of IPEC-J2/FBS (n = 7) and IPEC-J2/PS (n = 8). (B) Permeability ratio for sodium and chloride (PNa/PCl), indicating paracellular charge selectivity, as determined by dilution potentials measurements ...
Juliane Rieger (485685), Silke S. Zakrzewski (485681), In-Fah M. Lee (485684), Jan F. Richter (485682), Susanne M. Krug (181168), Jörg D. Schulzke (354049), Britta Jebautzke (485683), Monika Sachtleben (485686), Angelika Bondzio (430493), Michael Fromm (23852), Dorothee Günzel (208959)   +10 more
core   +1 more source

Immunofluorescent staining of claudin-4 in control and MI-432-treated IPEC-J2 cells grown on Transwell polyester membrane insert.

, 2015
Cell monolayers were incubated with plain DMEM (control) or MI-432 (treated) for 48 hours, and then cells were labelled for claudin-4 and cell nuclei were stained with DAPI in blue. IPEC-J2 cells showed homogenous, intense membranous claudin-4 positivity
S. McManus (816856), P. Gálfi (816859), T. Steinmetzer (816860), P. Balla (816858), N. Meggyesházi (816857), E. Pászti-Gere (816855)   +5 more
core   +1 more source

Tea Polyphenols Relieve the Fluoride-Induced Oxidative Stress in the Intestinal Porcine Epithelial Cell Model

Toxics
Prolonged excessive intake of fluoride (F) can result in fluorosis, leading to a range of tissue oxidative damages. Therefore, mitigating the oxidative stress induced by fluorosis has become a significant research concern.
Chunyan Xie, Shuyi Niu, Wen Tian
doaj   +1 more source

Correction: Trolox and Ascorbic Acid Reduce Direct and Indirect Oxidative Stress in the IPEC-J2 Cells, an In Vitro Model for the Porcine Gastrointestinal Tract

, 2015
Correction: Trolox and Ascorbic Acid Reduce Direct and Indirect Oxidative Stress in the IPEC-J2 Cells, an In Vitro Model for the Porcine Gastrointestinal ...
PLOS ONE (2189197)
core   +1 more source

H₂O₂ and DEM affect the tight junction distribution in IPEC-J2 cells.

, 2015
Immunocytochemical staining with ZO-1 of IPEC-J2 cells was performed to investigate the effect of A: no treatment, B: 1 mM H2O2 or C: 4 mM DEM for 1 h on the tight junction distribution.
Hans Vergauwen (728135), Stefaan De Smet (590492), Chris Van Ginneken (728140), Bart Tambuyzer (728136), Jeroen Degroote (728138), Karen Jennes (728137), Wei Wang (17594), Joris Michiels (728139)   +7 more
core   +1 more source

Porcine Epidemic Diarrhea Virus Infection of Porcine Intestinal Epithelial Cells Causes Mitochondrial DNA Release and the Activation of the NLRP3 Inflammasome to Mediate Interleukin-1β Secretion

Veterinary Sciences
Porcine epidemic diarrhea virus (PEDV) induces enteritis and diarrhea in piglets. Mitochondrial DNA (mtDNA) contributes to virus-induced inflammatory responses; however, the involvement of inflammasomes in PEDV infection responses remains unclear.
Di Bao, Shushuai Yi, Luobing Zhao, Han Zhao, Jiuyuan Liu, Yiming Wei, Guixue Hu, Xinxin Liu   +7 more
doaj   +1 more source

Dynamic Mechanical Load as a Trigger for Growth and Proliferation in Porcine Epithelial Cells

Biomolecules
The impact of gravity is a basic force determining our existence on Earth. Changes in orientation with respect to the gravity vector trigger alternating mechanical forces on organisms, organs, and cells. In the intestines of mammals, epithelial cells are
Stefan Kahlert, Constanze Nossol, Marcus Krüger, Sascha Kopp, Daniela Grimm, Simon L. Wuest, Hermann-Josef Rothkötter   +6 more
doaj   +1 more source

Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway

, 2019
The aim of this study was to investigate the effects of deoxynivalenol (DON) exposure on the inflammatory injury nuclear factor kappa-B (NF-κB) pathway in intestinal epithelial cells (IPEC-J2 cells) of pig.
Yafei Zhang, Sajid Ur Rahman, Li Cao, Jie Zhao, Yingying Huang, Yu Li, Xiaofang Chen, Xichun Wang, Lei Zhu, Shibin Feng, Jinjie Wu   +10 more
core   +1 more source

Effect of L. rhamnosus on apoptosis of IPEC-J2 cells.

, 2015
IPEC-J2 cells were collected from the indicated cultures at 3 h after F4+ ETEC challenge. Apoptosis was assessed by flow cytometry. (A) Representative two-dimensional scatter plots of annexin V versus propidium iodide.
Gui-Yan Yang (730843), Wei Zhang (405), Yao-Hong Zhu (313560), Jin-Cai Yang (313568), Jiu-Feng Wang (313570), Dong Zhou (313567)   +5 more
core   +1 more source