Results 111 to 120 of about 5,753 (209)

Entry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis

Virology Journal, 2019
Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, are a significant cause of enteritis, pneumonia, polioencephalomyelitis and reproductive disorders in pigs. However, the life cycle of PSV on the molecular level is largely unknown.Here, we used chemical inhibitors, RNA interference, and overexpression of ...
Tingting Zhao, Li Cui, Xiangqian Yu, Zhonghai Zhang, Xiaojuan Shen, Xiuguo Hua   +5 more
openaire   +3 more sources

In vitro penetration of the antibiotic fosfomycin in swine intestinal cells (IPEC J2) [PDF]

, 2013
Fosfomycin is an antibiotic widely used for the treatment and prevention of swine infections caused by resistant bacteria. The aim of this research was to study the penetration of fosfomycin in an in vitro model of intestinal cells (IPEC-J2 cells). Cells
Martínez, Guadalupe, Pérez, Denisa Soledad, Soraci, Alejandro Luis, Tapia, Maria Ofelia   +3 more
core   +1 more source

The GadX regulon affects virulence gene expression and adhesion of porcine enteropathogenic Escherichia coli in vitro [PDF]

, 2017
The ability of enteropathogenic Escherichia coli (EPEC) to express virulence factor genes and develop attaching and effacing (AE) lesions is inhibited in acidic environmental conditions.
Aschenbach, Jörg R., Bauerfeind, Rolf, Braun, Hannah-Sophie, Deiner, Carolin, Kerner, Katharina, Sponder, Gerhard   +5 more
core   +1 more source

Overcoming Clinical Barriers: Utilizing Self‐Assembly Systems to Break the Protease Limitations of Antimicrobial Peptides

Aggregate, Volume 6, Issue 12, December 2025.
This study addresses AMPs' clinical application challenges by enhancing stability via molecular assembly. Pba* shows high antibacterial activity, biocompatibility, and low toxicity, paving the way for antimicrobial materials. ABSTRACT Natural antimicrobial peptides (AMPs) encounter significant challenges in transitioning to clinical application ...
Xu Guo, Weikang Yu, Qingrui Li, Xuefeng Li, Yingxin Wei, Jiajun Wang, Yinfeng Lyu, Anshan Shan   +7 more
wiley   +1 more source

Modelling ferroptosis in IPEC-J2 cells: insights into iron-dependent cell death

Italian Journal of Animal Science
Ferroptosis, a form of regulated cell death characterised by iron accumulation and lipid peroxidation, plays a crucial role in various diseases. However, its mechanisms in livestock, particularly in pigs, remain unclear. In this study, we established an in vitro ferroptosis model using the porcine intestinal epithelial cell line IPEC-J2 to investigate ...
Ching-Hsuan Liu, Yuan-Yu Lin
openaire   +2 more sources

Deoxynivalenol Inhibits Porcine Intestinal Trefoil Factors Expression in Weanling Piglets and IPEC-J2 Cells [PDF]

Toxins, 2019
Trefoil factors (TFFs) are regulatory peptides playing critical roles in mucosal repair and protection against a variety of insults within the gastrointestinal tract. This work aimed to explore the effects of deoxynivalenol (DON) on intestinal TFFs expression using in vivo and in vitro models.
Shuai Wang, Cong Zhang, Xu Wang, Jiacheng Yang, Kuntan Wu, Jiacai Zhang, Beiyu Zhang, Ao Yang, Desheng Qi   +8 more
openaire   +3 more sources

Spirobenzofuran Mitigates Ochratoxin A-Mediated Intestinal Adverse Effects in Pigs through Regulation of Beta Defensin 1

Toxics
Antimicrobial peptides (AMPs) function to extensively suppress various problematic factors and are considered a new alternative for improving livestock health and enhancing immunomodulation.
Jung Woong Yoon, Myoung Ok Kim, Sangsu Shin, Woo-Sung Kwon, Soo Hyun Kim, Yun-Ju Kwon, Sang In Lee   +6 more
doaj   +1 more source

Gamma‐Glutamyl‐Cysteine Alleviates Inflammatory Bowel Disease by Suppressing the NF‐κB Pathway in Jejunum and Modulating the Gut Microbiota

eFood, Volume 6, Issue 6, December 2025.
Gamma‐glutamyl‐cysteine (γ‐EC) has the potential to enhance the regulatory functions of the jejunal barrier by increasing the expression of tight junction proteins and inhibiting the expression of NF‐κB pathway proteins, and to alleviate inflammation by maintaining the level of intestinal short‐chain fatty acids through an increase in the population of
Shiyan Jian, Zhongquan Xin, Yixuan Xie, Kang Yang, Limeng Zhang, Xiaoying Jian, Xinye Lin, Lingna Zhang, Sufang Han, Jinping Deng, Baichuan Deng   +10 more
wiley   +1 more source

Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells [PDF]

, 2016
Oregano essential oil (OEO) has long been used to improve the health of animals, particularly their intestinal health. The health benefits of OEO are generally attributed to antioxidative actions, but the mechanisms remain unclear.
Hongkui Wei, Jian Peng, Jun Wang, Yi Zou
core   +2 more sources

Extraction, Structural Characterization and Biological Activities of Polysaccharides Derived From Hericium erinaceus

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This review summarizes the methods used to extract and purify H. erinaceus polysaccharides (HEP), primarily hot water extraction and column chromatography. Structural characterization indicates that the molecular weights of HEP range from 2.1 to 75,000 kDa, with glucose as the dominant monosaccharide and β‐glycosidic bonds, notably β‐glucans with 1 → 3
Naxin Sun, Chao Li, Wu Liang, Zijian Wu, Xuemei Han, Suyun Xu   +5 more
wiley   +1 more source