Results 1 to 10 of about 5,250,485 (203)

TLR/MyD88-Mediated Inflammation Induced in Porcine Intestinal Epithelial Cells by Ochratoxin A Affects Intestinal Barrier Function [PDF]

Toxics, 2023
The intestinal epithelium performs vital functions such as nutrient absorption and acting as an intestinal barrier to maintain the host’s homeostasis. Mycotoxin, which affects the processing and storage of animal feedstuff, is a problematic pollutant in ...
Jung Woong Yoon, Sangsu Shin, JeongWoong Park, Bo Ram Lee, Sang In Lee   +4 more
doaj   +3 more sources

Infection of porcine enteroids and 2D differentiated intestinal epithelial cells with rotavirus A to study cell tropism and polarized immune response

Emerging Microbes and Infections, 2023
Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan, Ang Su, Suvarin Pavasutthipaisit, Rebecca Spriewald, Guntram A. Graßl, Andreas Beineke, Doris Hoeltig, Georg Herrler, Paul Becher   +8 more
doaj   +3 more sources

Butyrate limits the replication of porcine epidemic diarrhea virus in intestine epithelial cells by enhancing GPR43-mediated IFN-III production [PDF]

Frontiers in Microbiology, 2023
Porcine epidemic diarrhea virus (PEDV) is a threat to the health of newborn piglets and has a significant impact on the swine industry. Short-chain fatty acids (SCFAs) are gut microbial metabolites that regulate intestinal function through different ...
Haiyan He, Haiyan He, Xuelei Fan, Xuelei Fan, Haiyan Shen, Haiyan Shen, Haiyan Shen, Hongchao Gou, Hongchao Gou, Hongchao Gou, Chunhong Zhang, Chunhong Zhang, Chunhong Zhang, Zhicheng Liu, Zhicheng Liu, Zhicheng Liu, Zhicheng Liu, Bin Zhang, Bin Zhang, Nile Wuri, Nile Wuri, Jianfeng Zhang, Jianfeng Zhang, Jianfeng Zhang, Ming Liao, Ming Liao, Ming Liao, Letu Geri   +27 more
doaj   +2 more sources

A Functional Variant in the Aquaporin-3 Promoter Modulates Its Expression and Correlates With Resistance to Porcine Epidemic Virus Infection in Porcine Intestinal Epithelial Cells [PDF]

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) causes a highly contagious intestinal disease in neonatal pigs. Aquaporin-3 (AQP3) plays important roles in maintenance of intestinal barrier function and regulation of immune responses.
Haifei Wang, Zhenbin Bi, Kaiyu Dai, Pinghua Li, Ruihua Huang, Shenglong Wu, Shenglong Wu, Wenbin Bao, Wenbin Bao   +8 more
doaj   +2 more sources

Stanniocalcin-1 Overexpression Protects Porcine Intestinal Epithelial Cells Against TBHP-Induced Oxidative Stress by Preserving Mitochondrial Homeostasis [PDF]

Animals
Stanniocalcin-1 (STC-1) is a multifunctional glycoprotein; however, its role in protecting intestinal epithelial cells against oxidative injury has not been completely elucidated.
Liming Wu, Yan Bin, Yubei Wei, Zihan Cui, Jiayi Du, Jinluo Lv, Xiaoliang Xiang   +6 more
doaj   +2 more sources

Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection

Viruses, 2023
Various coronaviruses have emerged as a result of cross-species transmission among humans and domestic animals. Porcine epidemic diarrhea virus (PEDV; family Coronaviridae, genus Alphacoronavirus) causes acute diarrhea, vomiting, dehydration, and high ...
Zheng Niu, Shujuan Zhang, Shasha Xu, Jing Wang, Siying Wang, Xia Hu, Li Zhang, Lixin Ren, Jingyi Zhang, Xiangyang Liu, Yang Zhou, Liu Yang, Zhenhui Song   +12 more
doaj   +2 more sources

Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells

Toxins, 2023
Under natural conditions, T-2 toxin can be easily metabolized to HT-2 toxin by deacetylation, and T-2 and HT-2 are usually co-contaminated in grain and feed at a high detected rate.
Weihua He, Jianhua Wang, Mengyi Han, Lihua Wang, Ling Li, Jiahui Zhang, Siqi Chen, Jiayi Guo, Xiaohu Zhai, Junhua Yang   +9 more
doaj   +3 more sources

Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Frontiers in Immunology, 2022
Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to ...
Yue Yin, Jinglin Ma, Cliff Van Waesberghe, Bert Devriendt, Herman W. Favoreel   +4 more
doaj   +1 more source

Analysis of Intestinal Mucosa Integrity and GLP-2 Gene Functions upon Porcine Epidemic Diarrhea Virus Infection in Pigs

Animals, 2021
Porcine epidemic diarrhea virus (PEDV) infects intestinal epithelial cells, destroys the intestinal mucosal barrier and then causes diarrhea in piglets.
Yajing Zhou, Zhanshi Ren, Shuai Zhang, Haifei Wang, Shenglong Wu, Wenbin Bao   +5 more
doaj   +1 more source

Effects of Deoxynivalenol and Mycotoxin Adsorbent Agents on Mitogen-Activated Protein Kinase Signaling Pathways and Inflammation-Associated Gene Expression in Porcine Intestinal Epithelial Cells [PDF]

Toxins, 2021
Yeong-Hsiang Cheng, Yu-Hsiang Yu, Felix Shih-Hsiang Hsiao   +2 more
exaly   +2 more sources