Results 111 to 120 of about 18,891 (223)

Transforming Fragile Hydrogel Chips Into Standardized Cartridges via Contact Line Pinning for Robust Microfluidics

Small, EarlyView.
Hydrogel‐based microfluidic chips revolutionize drug delivery, tissue engineering, and biosensing, yet face challenges due to fragility and connection difficulty. This study introduces a novel cartridge design that enhances usability through a hydrogel–plastic hybrid design and a contactless connection method.
Sin‐Yung Siu, Chiu‐Wing Chan, Yisu Wang, Langcheng Feng, Yichen Su, Yin Chen, Christopher K C LAI, Pingan Zhu, Kangning Ren   +8 more
wiley   +1 more source

Self‐Healing and pH‐Robust Hydrogels Enabled by Synergistic Supramolecular Interactions for Injectable Gastrointestinal Wound Repair

Small, EarlyView.
A pH‐robust injectable hydrogel enabled by synergistic supramolecular interactions is developed to address the intrinsic limitations of conventional hydrogel dressings in complex gastrointestinal environments. By actively leveraging environmental stimuli to regulate functionality, this supramolecular synergy strategy provides a versatile platform for ...
Li Xiang, Lei Liu, Shixin Zhang, Yuhao Zhang, Ziqian Zhao, Jiangwei Chen, Jiawen Zhang, Jingyi Hu, Yunfei Chen, Hongbo Zeng   +9 more
wiley   +1 more source

Relationship Between Fecal Bile Acid Profile and Intestinal Microbiota in Patients With Chronic Radiation Enteritis

Journal of Digestive Diseases, EarlyView.
Patients with chronic radiation enteritis (CRE) demonstrate dysregulated bile acid (BA) metabolism, characterized by an increased proportion of primary BAs and a decreased proportion of secondary BAs. Moreover, the diversity of the intestinal microbiota is significantly reduced in individuals with CRE, and there is a bidirectional interaction between ...
Xin Shen, Song Bo Li, Meng Jie Gao, Jiao Jiao Cao, Hua Yang, Wei Wei Li, Li Chun Wei, Min Chen, Jun Ye Liu, Yong Quan Shi   +9 more
wiley   +1 more source

Molecular mechanism of valine and its metabolite in improving triglyceride synthesis of porcine intestinal epithelial cells. [PDF]

Sci Rep, 2023
Xu M, Che L, Niu L, Wang L, Li M, Jiang D, Deng H, Chen W, Jiang Z.   +8 more
europepmc   +1 more source

Lycopene alleviates Deoxynivalenol-induced toxicity in Porcine intestinal epithelial cells by mediating mitochondrial function

Toxicology
Abstract Deoxynivalenol (DON) is widely found in food and feed, posing a threat to human and animal health. Lycopene (Lyc) is a natural plant extracts with significant antioxidant properties. This study was conducted to investigate the protective effects of Lyc on IPEC-J2 cells upon DON exposure.
Jie, Wang, Fan, Lu, Shanshen, Gu, Changfu, Cao, Yeyi, Xiao, Wenbin, Bao, Haifei, Wang   +6 more
openaire   +2 more sources

Integrating Dialysis in Ex Situ Machine Perfusion: A Systematic Review and Meta‐Analysis of Outcomes

Artificial Organs, EarlyView.
Dialysis‐enhanced EVMP effectively maintains biochemical homeostasis, potentially mitigating metabolic stress and extending perfusion duration. Functional outcomes varied depending on the organ type, with the most pronounced benefits observed in cardiac perfusion.
Yomna E. Dean, Sean Frisbie, James Gaston, Diwakar Phuyal, Bahareh Tabatabaei, Florian Huwyler, Matthias Pfister, Jonas Binz, Antonio Rampazzo, Gábor Szabó, Mark W. Tibbit, Pierre‐Alain Clavien, Bahar Bassiri Gharb   +12 more
wiley   +1 more source

PEDV infection downregulates goblet cell differentiation through activating the Notch pathway

Veterinary Research
Porcine epidemic diarrhoea virus (PEDV) is the most widespread porcine coronavirus worldwide, causing high mortality and a high incidence rate among piglets.
Yi Wang, Shanshan Yang, Yongxiang Zhao, Shuo Tian, Qiuxia Cao, Xinmei Geng, Mengdi Yang, Xu Song, Hongqi Shang, Shiyu Liu, Rongli Guo, Yunchuan Li, Min Sun, Mi Hu, Baochao Fan, Bin Li   +15 more
doaj   +1 more source

Analysis of RIOK2 Functions in Mediating the Toxic Effects of Deoxynivalenol in Porcine Intestinal Epithelial Cells. [PDF]

Int J Mol Sci, 2022
Gao Z, Xu C, Fan H, Wang H, Wu Z, Wu S, Bao W.   +6 more
europepmc   +1 more source

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract

The FEBS Journal, EarlyView.
Nitrate from food is first converted to nitrite by oral bacteria and then further processed in the intestine. The gut microbiota reduces nitrate and nitrite to ammonia or nitric oxide, preventing the formation of carcinogenic nitrosamines. Our analysis highlights Escherichia coli as a key player in this detoxification process, supported by other ...
Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean‐Lou Christian Michel Dorne, Uwe Deppenmeier   +4 more
wiley   +1 more source

Analysis of the Roles of the ISLR2 Gene in Regulating the Toxicity of Zearalenone Exposure in Porcine Intestinal Epithelial Cells. [PDF]

Toxins (Basel), 2022
Bi Z, Gu X, Xiao Y, Zhou Y, Bao W, Wu S, Wang H.   +6 more
europepmc   +1 more source