Results 101 to 110 of about 5,250,485 (203)

Epithelial induction of porcine suppressor of cytokine signaling 2 (SOCS2) gene expression in response to Entamoeba histolytica

, 2010
International audienceSuppressor of cytokine signaling (SOCS) proteins are key physiological regulators of both innate and adaptive immunity. These proteins belong to the three major classes of modulators of cytokines signaling. In the following article,
Salmon, Henri, H., Henri Salmon, Fabienne Girard-Misguich, Meurens, Francois, Melo, Sandrina, François Meurens, Sandrine Melo, Timothée Bruel, Roseline Guibon, Nancy Guillén, Guillén, Nancy, Guibon, Roseline, Girard-Misguich, Fabienne, Bruel, Timothée   +13 more
core   +1 more source

Rapid progesterone actions on thymulin-secreting epithelial cells cultured from rat thymus [PDF]

, 1999
Many soluble factors of neural, endocrine, paracrine and autocrine origin are present in the thymus and modulate its function. Long-term effects of sex steroids have! been documented for thymocytes and cells of the thymic microenvironment. In this report
Downing, James E. G., Brucker, Cosima, Mentlein, Rolf, Kendall, Marion D., Head, Gail M.   +4 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

Andrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz, Annika Liebich, Youli Stepanov, Jan B. Stöckl, Mirko Peitzsch, Michaela Schneider, Julia Schneider, Nicole Kreitmair, Matthias Trottmann, Frank‐Michael Köhn, Jovica Ninkovic, Thomas Fröhlich, Artur Mayerhofer   +12 more
wiley   +1 more source

Modelling ferroptosis in IPEC-J2 cells: insights into iron-dependent cell death

Italian Journal of Animal Science
Ferroptosis, a form of regulated cell death characterised by iron accumulation and lipid peroxidation, plays a crucial role in various diseases. However, its mechanisms in livestock, particularly in pigs, remain unclear.
Ching-Hsuan Liu, Yuan-Yu Lin
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Magnolol inhibits porcine epidemic diarrhea virus infection by suppressing cathepsin L expression in vitro and in vivo

Journal of Virology
Porcine epidemic diarrhea (PED), caused by the porcine epidemic diarrhea virus (PEDV), is an acute and highly contagious intestinal disease in pigs. The high variability of the PEDV S gene has rendered current commercial vaccines ineffective, indicating ...
Yi-fan Liang, Xi Li, Gao-xi Zhu, Yi Song, Xiong-nan Chen, Heng Wang, Gui-hong Zhang   +6 more
doaj   +1 more source

Effects of N‐Acetylcysteine on Oxidative Status and Intestinal Health in Piglets (Sus scrofa domesticus L.): A PRISMA‐Based Systematic Review

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Oxidative stress is a critical challenge in intensive swine production, particularly during weaning, compromising intestinal integrity and animal performance. N‐acetylcysteine (NAC) has emerged as a multifunctional nutritional strategy to mitigate these effects due to its role as a glutathione precursor and signaling modulator. This systematic
Jessica Lucilene Cantarini Buchini, Karoline Silva de Camargo, Lucas Rocha Valfré, Núbia Michelle Vieira da Silva, Rodrigo Garófallo Garcia, Vivian Aparecida Rios e Castilho Heiss, Claudia Marie Komiyama, Fabiana Ribeiro Caldara   +7 more
wiley   +1 more source

Number of intestinal epithelial cells expressing AJPs.

, 2019
Number of intestinal epithelial cells expressing AJPs.
Yeon-Jung Seo (6818165), Karin Allenspach (335040), Chong Wang (120449), Jonathan P. Mochel (6102389), Giacomo Rossi (550003), Robin White (76628), Mary Breuer (8201169), Mark Ackermann (2165995), Todd Atherly (2166001), Albert E. Jergens (6887375)   +9 more
core   +1 more source