Results 11 to 20 of about 18,891 (223)

Infection of porcine enteroids and 2D differentiated intestinal epithelial cells with rotavirus A to study cell tropism and polarized immune response

open access: yesEmerging Microbes and Infections, 2023
Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan   +8 more
doaj   +1 more source

Butyrate limits the replication of porcine epidemic diarrhea virus in intestine epithelial cells by enhancing GPR43-mediated IFN-III production

open access: yesFrontiers in Microbiology, 2023
Porcine epidemic diarrhea virus (PEDV) is a threat to the health of newborn piglets and has a significant impact on the swine industry. Short-chain fatty acids (SCFAs) are gut microbial metabolites that regulate intestinal function through different ...
Haiyan He   +27 more
doaj   +1 more source

Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

open access: yesFrontiers in Immunology, 2022
Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to ...
Yue Yin   +4 more
doaj   +1 more source

Analysis of Intestinal Mucosa Integrity and GLP-2 Gene Functions upon Porcine Epidemic Diarrhea Virus Infection in Pigs

open access: yesAnimals, 2021
Porcine epidemic diarrhea virus (PEDV) infects intestinal epithelial cells, destroys the intestinal mucosal barrier and then causes diarrhea in piglets.
Yajing Zhou   +5 more
doaj   +1 more source

Effects of Lactobacillus rhamnosus DSM7133 on Intestinal Porcine Epithelial Cells

open access: yesAnimals, 2023
Antimicrobial resistance is one of the biggest health challenges nowadays. Probiotics are promising candidates as feed additives contributing to the health of the gastrointestinal tract. The beneficial effect of probiotics is species/strain specific; the potential benefits need to be individually assessed for each probiotic strain or species.
Nikolett Palkovicsné Pézsa   +7 more
openaire   +3 more sources

Porcine IPEC-J2 intestinal epithelial cells in microbiological investigations [PDF]

open access: yesVeterinary Microbiology, 2012
IPEC-J2 cells are porcine intestinal columnar epithelial cells that were isolated from neonatal piglet mid-jejunum. This cell line forms polarized monolayers with high transepithelial electrical resistance when cultured on 0.4 μm pore-size filters. The cell line is unique in that it is derived from small intestinal tissue (compared to the common human ...
Amanda J, Brosnahan, David R, Brown
openaire   +2 more sources

Gentamicin sulphate permeation through porcine intestinal epithelial cell monolayer [PDF]

open access: yesActa Veterinaria Hungarica, 2015
Gentamicin is an aminoglycoside antibiotic widely used in combination with dimethyl sulphoxide (DMSO) in topical drug formulations. It is not known, however, whether DMSO can enhance the permeation of gentamicin through biological membranes, leading to oto- and nephrotoxic side effects.
Gyetvai, Béla   +4 more
openaire   +3 more sources

Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection

open access: yesViruses, 2023
Various coronaviruses have emerged as a result of cross-species transmission among humans and domestic animals. Porcine epidemic diarrhea virus (PEDV; family Coronaviridae, genus Alphacoronavirus) causes acute diarrhea, vomiting, dehydration, and high ...
Zheng Niu   +12 more
doaj   +1 more source

Characteristic and functional analysis of a newly established porcine small intestinal epithelial cell line. [PDF]

open access: yesPLoS ONE, 2014
The mucosal surface of intestine is continuously exposed to both potential pathogens and beneficial commensal microorganisms. Recent findings suggest that intestinal epithelial cells, which once considered as a simple physical barrier, are a crucial cell
Jing Wang   +5 more
doaj   +1 more source

Porcine intraepithelial lymphocytes undergo migration and produce an antiviral response following intestinal virus infection

open access: yesCommunications Biology, 2022
When piglets are infected with intestinal virus, porcine intraepithelial lymphocytes undergo intra-and trans-epithelial migration promoted by chemokines from infected epithelial cells and produce an antiviral response.
Yuchen Li   +8 more
doaj   +1 more source

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