Results 41 to 50 of about 5,487 (206)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +2 more sources

First identification of porcine parvovirus 6 in Poland [PDF]

, 2016
Porcine parvovirus type 1 is a major causative agent of swine reproductive failure. During the past decade, several new parvoviruses have been discovered in pigs.
Tanja Opriessnig, Chao-Ting Xiao, Gerber, Priscilla Freitas, Biernacka, Kinga, Kinga Biernacka, Priscilla F. Gerber, Xiao, Chao-Ting, Tomasz Stadejek, Biernacka , Kinga, Jin Cui, Cui, Jin, Stadejek, Tomasz, Jinghui Fan, Fan, Jinghui, Freitas Gerber, Priscilla, Opriessnig, Tanja   +15 more
core   +1 more source

Determination of optimum nanofiltration conditions for the manufacturing process of human normal immunoglobulin G for intravenous administration

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Medicinal products based on immunoglobulin class G (IgG) from human plasma are widely used in clinical practice to treat bacterial and viral infections, primary and secondary immunodeficiencies, and autoimmune diseases ...
N. V. Zubkova, A. M. Nikolaeva, A. V. Ivanov, O. V. Beliakova, M. V. Razumikhin, N. V. Vinokurova, I. S. Efimova, T. I. Smolyanova, E. I. Sakanyan   +8 more
doaj   +1 more source

Discovery of Novel Viruses and Common Contaminants From Unmapped DNA and RNA in Pigs and Chickens Under Different Housing Conditions

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Unmapped sequencing reads in livestock often contain valuable information about pathogens but are typically discarded. We analyzed blood‐derived DNA and RNA from chickens and pigs kept under high‐ and low‐biosecurity conditions, focusing on unmapped reads.
Martijn F. L. Derks, Bert Dibbits, Richard P. M. A. Crooijmans, Kim Lensing   +3 more
wiley   +1 more source

Differential expression of microRNAs in porcine parvovirus infected porcine cell line [PDF]

Virology Journal, 2015
Porcine parvovirus (PPV), a member of the Parvoviridae family, causes great economic loss in the swine industry worldwide. MicroRNAs (miRNAs) are a class of non-protein-coding genes that play many diverse and complex roles in viral infections.Aiming to determine the impact of PPV infections on the cellular miRNAome, we used high-throughput sequencing ...
Li, Xinqiong, Zhu, Ling, Liu, Xiao, Sun, Xiangang, Zhou, Yuanchen, Lang, Qiaoli, Li, Ping, Cai, Yuhan, Qiao, Xiaogai, Xu, Zhiwen   +9 more
openaire   +2 more sources

Co-Infection of Swine with Porcine Circovirus Type 2 and Other Swine Viruses

Viruses, 2019
Porcine circovirus 2 (PCV2) is the etiological agent that causes porcine circovirus diseases and porcine circovirus-associated diseases (PCVD/PCVAD), which are present in every major swine-producing country in the world.
Ting Ouyang, Xinwei Zhang, Xiaohua Liu, Linzhu Ren   +3 more
doaj   +1 more source

SAT: a Late NS Protein of Porcine Parvovirus [PDF]

Journal of Virology, 2005
ABSTRACT The genomes of all members of the Parvovirus genus were found to contain a small open reading frame (ORF), designated SAT, with a start codon four or seven nucleotides downstream of the VP2 initiation codon.
Zoltán, Zádori, József, Szelei, Peter, Tijssen   +2 more
openaire   +2 more sources

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Interclade recombination in porcine parvovirus strains

Journal of General Virology, 2012
A detailed analysis of the Ns1/Vp1Vp2 genome region of the porcine parvovirus (PPV) strains isolated from vaccinated animals was performed. We found many inconsistencies in the phylogenetic trees of these viral isolates, such as low statistical support and strains with long branches in the phylogenetic trees. Thus, we used distance-
Élcio, Leal, Fabiola E, Villanova, Wencheng, Lin, Feng, Hu, Qinfang, Liu, Yebing, Liu, Shangjin, Cui   +6 more
openaire   +2 more sources