Results 51 to 60 of about 2,648 (172)

Protease-Independent Production of Poliovirus Virus-like Particles in Pichia pastoris: Implications for Efficient Vaccine Development and Insights into Capsid Assembly

open access: yesMicrobiology Spectrum, 2023
The production of enterovirus virus-like particles (VLPs) that lack the viral genome have great potential as vaccines for a number of diseases, such as poliomyelitis and hand, foot, and mouth disease.
Lee Sherry   +7 more
doaj   +1 more source

A new familial form of a late-onset, persistent hyperinsulinemic hypoglycemia of infancy caused by a novel mutation in KCNJ11. [PDF]

open access: yes, 2017
The ATP-sensitive potassium channel (KATP) functions as a metabo-electric transducer in regulating insulin secretion from pancreatic β-cells. The pancreatic KATP channel is composed of a pore-forming inwardly-rectifying potassium channel, Kir6.2, and a ...
Ferrara, Christine   +5 more
core   +1 more source

Establishing Polycistronic Expression in the Model Microorganism Ustilago maydis

open access: yesFrontiers in Microbiology, 2020
Eukaryotic microorganisms use monocistronic mRNAs to encode proteins. For synthetic biological approaches like metabolic engineering, precise co-expression of several proteins in space and time is advantageous.
Kira Müntjes   +7 more
doaj   +1 more source

MultiBac: expanding the research toolbox for multiprotein complexes [PDF]

open access: yes, 2012
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Berger, Imre   +3 more
core   +1 more source

The Avian Encephalomyelitis Virus (AEV) 5’ Untranslated Region Contains an IRES with Similarity to the Hepatitis C Virus IRES [PDF]

open access: yesIranian Journal of Public Health, 2005
Cap-independent internal initiation of protein synthesis has been shown to occur on a number of viral and cellular mRNAs. Initiation of protein synthesis is directed by an internal ribosome entry site (IRES) element within the 5’ untranslated region (UTR)
M Bakhshesh, L Roberts, G J Belsham
doaj   +2 more sources

Epidemiologic investigation of immune-mediated polyradiculoneuropathy among abattoir workers exposed to porcine brain [PDF]

open access: yes, 2003
Background In October 2007, a cluster of patients experiencing a novel polyradiculoneuropathy was identified at a pork abattoir (Plant A). Patients worked in the primary carcass processing area (warm room); the majority processed severed heads (head ...
Holzbauer, Stacy M.   +21 more
core   +2 more sources

SPLICEIT Fluorescent Sensor for Integrating Dopamine Release with Cellular Resolution

open access: yesAngewandte Chemie, Volume 137, Issue 33, August 11, 2025.
“Single‐chain protein‐based ligand indication through a chimerically‐engineered integrator tool” (SPLICEIT) is a G‐protein coupled receptor‐based sensor design that leaves a permanent fluorescent mark. We show dopamine detection in primary cultured neurons with a fourfold signal increase normalized to an mCherry (mCh) marker.
Steven M. Havens   +7 more
wiley   +2 more sources

Molecular survey of porcine teschovirus, porcine sapelovirus, and enterovirus G in captive wild boars (Sus scrofa scrofa) of Paraná state, Brazil

open access: yesPesquisa Veterinária Brasileira, 2015
Porcine teschovirus (PTV), porcine sapelovirus (PSV), and enterovirus G (EV-G) are infectious agents specific to pig host species that are endemically spread worldwide.
Daiane G. Donin   +4 more
doaj   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

open access: yesAngewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe   +7 more
wiley   +1 more source

Detection of Porcine Teschovirus and Enterovirus Type II by Reverse Transcription–Polymerase Chain Reaction [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 2002
Porcine enteroviruses (PEVs) have been recognized as the causative agents of various clinical manifestations such as fertility disorders, neurological defects, and dermal lesions in pigs. Currently, the diagnosis of PEV infection is carried out by virus isolation, which although useful, is labor- and time-intensive. The present investigation describes
Joseph M, Palmquist   +4 more
openaire   +2 more sources

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