Results 61 to 70 of about 1,688 (163)

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Complete coding genome sequence of a putative novel teschovirus serotype 12 strain

, 2016
Porcine teschoviruses are ubiquitous and prevalent viruses generally harmless to their hosts, the suids. Here, we report the first complete coding genome sequence of a putative new serotype of porcine teschovirus (PTV-12), strain CC25, isolated from ...
Jiménez-Clavero, Miguel Ángel, Cano-Gómez, Cristina   +1 more
core   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, Volume 65, Issue 22, 25 May 2026.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Swine polioencephalomyelitis in Brazil: identification of Teschovirus A, Sapelovirus A, and Enterovirus G in a farm from Southern Brazil

, 2021
Porcine encephalomyelitis can be associated with many etiologies, including viral agents, such as Porcine teschovirus (PTV), Porcine sapelovirus (PSV), and Porcine astrovirus (PoAstV).
Schwertz, Claiton Ismael, Pavarini, Saulo Petinatti, de Almeida, Paula Rodrigues, Caprioli, Rafaela Albuquerque, Cruz, Raquel Aparecida Sales da, Spilki, Fernando Rosado, de Cecco, Bianca Santana, Almeida, Paula Rodrigues de, Cecco, Bianca Santana de, Hammerschmitt, Márcia Elisa, Lorenzett, Marina Paula, Demoliner, Meriane, Driemeier, David, Eisen, Ana Karolina Antunes, da Cruz, Raquel Aparecida Sales, Schuh, Daniela Teresa   +15 more
core   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of TCE‐secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, Volume 13, Issue 19, 2 April 2026.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

Strain, procedures, and tools for reproducible genetic transformation and genome editing of the emerging plant model Spirodela polyrhiza

New Phytologist, Volume 250, Issue 2, Page 735-756, April 2026.
Summary Duckweeds (Lemnaceae) have excellent potential for fundamental and applied research due to ease of cultivation, small size, and continuous fast clonal growth. However, their usage as model organisms and platforms for biotechnological applications is often limited by the lack of universal genetic manipulation methods necessary for transgene ...
Verónica Barragán‐Borrero, Amanda de Santana Lopes, Enrico Diniz Rodrigues Batista, Martin Höfer, Rana Elias, Abhisek Chakraborty, Arturo Ponce‐Mañe, Clotilde Descombes, Laura Diezma‐Navas, Lydia Petraki, Meret Huber, Shuqing Xu, Arturo Marí‐Ordóñez   +12 more
wiley   +1 more source

The Adiponectin‐PP2A Pathway Confers Cognitive Benefits of Physical Exercise Against Chronic Stress‐Induced Tau Hyperphosphorylation in the Hippocampus

Aging Cell, Volume 25, Issue 3, March 2026.
Physical exercise ameliorates cognitive deficits and attenuates Tau hyperphosphorylation under chronic stress by elevating circulating adiponectin levels. Upon receptor binding, adiponectin modulates the LCMT1/PME‐1 regulatory axis to promote PP2A methylation and catalytic function.
Hui‐Hui Guo, Hai‐Ning Ou, Jia‐Sui Yu, Zi‐Rui Luo, Suk‐Yu Yau, Hector Wing‐Hong Tsang   +5 more
wiley   +1 more source

A Comprehensive Multiomics Approach Illuminates the Biosynthetic Mechanism of Scoparone in Artemisia capillaris

Plant Biotechnology Journal, Volume 24, Issue 1, Page 346-360, January 2026.
ABSTRACT Artemisia capillaris, a traditional Chinese medicinal plant, has displayed favourable effects in the treatment of jaundice, inflammation of the liver and cholecystitis for thousands of years. However, the biosynthesis of scoparone, the major active component in A. capillaris, remains unclear.
Fuyou Guo, Hong Zhou, Fangfang Yan, Junjie Chen, Qiuyu Zhu, Yu Tan, Yutong Guo, Xiangning Lai, Zongquan Li, Miao Zhang, Yi Ni, Matthana Klakong, Jiamin Yu, Liang Yang, Shili Li, Wei Ding   +15 more
wiley   +1 more source

Antigenic and immunogenic properties of industrial strains of Porcine Teschovirus

Agroecological journal, 2015
Досліджено 90 проб матеріалів головного та спинного мозку загиблих або вимушено забитих свиней з клінічними ознаками хвороби Тешена. Виділено 28 ізолятів вірусів. На підставі досліджень біологічних, фізико-хімічних, генетичних, антигенних та імуногенних властивостей штами Porcine teschovirus Дніпровський-34 та Городнянський-31 рекомендовано для ...
openaire   +3 more sources

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

Advanced Science, Volume 12, Issue 39, October 20, 2025.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin, Sheng‐Jia Lin, Yu Zhang, Kevin Huang, Cassidy Petree, Kevin Boyd, Pratishtha Varshney, Gaurav K. Varshney   +7 more
wiley   +1 more source