Results 111 to 120 of about 1,369,932 (286)

Video_3_Molecular and Functional Analysis of Pore-Forming Toxin Monalysin From Entomopathogenic Bacterium Pseudomonas entomophila.MOV

, 2020
Pseudomonas entomophila is a highly pathogenic bacterium that infects insects. It is also used as a suitable model pathogen to analyze Drosophila's innate immunity. P.
Emil Salim (8627832), Aki Hori (8627835), Rangga Meidianto Asri (8627841), Takumi Nishiuchi (449337), Shoji Takeuchi (114102), Saori Nonaka (8627829), Noriyuki Kodera (107990), Koki Kamiya (605693), Ayu Masyita (8627844), Takayuki Kuraishi (8627847), Firzan Nainu (8627838)   +10 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Purification of a 19-kDa pore-forming cytolysin from the sea anemone Heteractis magnifica

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Pore-forming cytolysins of 19 kDa from sea anemones present a remarkable cytolytic property. In the present work, a purified 19-kDa cytolysin was obtained from the sea anemone Heteractis magnifica.
S Karthikayalu, V Rama, R Venkatesan
doaj   +1 more source

Video_8_Molecular and Functional Analysis of Pore-Forming Toxin Monalysin From Entomopathogenic Bacterium Pseudomonas entomophila.MOV

, 2020
Pseudomonas entomophila is a highly pathogenic bacterium that infects insects. It is also used as a suitable model pathogen to analyze Drosophila's innate immunity. P.
Emil Salim (8627832), Aki Hori (8627835), Rangga Meidianto Asri (8627841), Takumi Nishiuchi (449337), Shoji Takeuchi (114102), Saori Nonaka (8627829), Noriyuki Kodera (107990), Koki Kamiya (605693), Ayu Masyita (8627844), Takayuki Kuraishi (8627847), Firzan Nainu (8627838)   +10 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins

Nature Communications
ABC toxins are toxin-translocating, pore-forming proteins found in a wide range of insecticidal bacteria and some mammalian pathogens. The Yersinia entomopahaga toxin complex (YenTc) belongs to a distinct subclass of ABC toxins, defined by a divergent ...
Yu Shang Low, Solace G. Roche, Nadezhda A. Aleksandrova, Gabriel Foley, Jason KK Low, Joseph K. Box, Tristan I. Croll, Irene R. Chassagnon, J. Shaun Lott, Evelyne Deplazes, Mikael Bodén, Mark RH Hurst, Sarah J. Piper, Michael J. Landsberg   +13 more
doaj   +1 more source

Video_5_Molecular and Functional Analysis of Pore-Forming Toxin Monalysin From Entomopathogenic Bacterium Pseudomonas entomophila.MOV

, 2020
Pseudomonas entomophila is a highly pathogenic bacterium that infects insects. It is also used as a suitable model pathogen to analyze Drosophila's innate immunity. P.
Emil Salim (8627832), Aki Hori (8627835), Rangga Meidianto Asri (8627841), Takumi Nishiuchi (449337), Shoji Takeuchi (114102), Saori Nonaka (8627829), Noriyuki Kodera (107990), Koki Kamiya (605693), Ayu Masyita (8627844), Takayuki Kuraishi (8627847), Firzan Nainu (8627838)   +10 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The Persistence-Inducing Toxin HokB Forms Dynamic Pores That Cause ATP Leakage

mBio, 2018
Bacterial populations harbor a small fraction of cells that display transient multidrug tolerance. These so-called persister cells are extremely difficult to eradicate and contribute to the recalcitrance of chronic infections.
Dorien Wilmaerts, Mariam Bayoumi, Liselot Dewachter, Wouter Knapen, Jacek T. Mika, Johan Hofkens, Peter Dedecker, Giovanni Maglia, Natalie Verstraeten, Jan Michiels   +9 more
doaj   +1 more source

Data_Sheet_1_Molecular and Functional Analysis of Pore-Forming Toxin Monalysin From Entomopathogenic Bacterium Pseudomonas entomophila.docx

, 2020
Pseudomonas entomophila is a highly pathogenic bacterium that infects insects. It is also used as a suitable model pathogen to analyze Drosophila's innate immunity. P.
Emil Salim (8627832), Aki Hori (8627835), Rangga Meidianto Asri (8627841), Takumi Nishiuchi (449337), Shoji Takeuchi (114102), Saori Nonaka (8627829), Noriyuki Kodera (107990), Koki Kamiya (605693), Ayu Masyita (8627844), Takayuki Kuraishi (8627847), Firzan Nainu (8627838)   +10 more
core   +1 more source