Results 31 to 40 of about 1,369,932 (286)
Repair of a Bacterial Small β-Barrel Toxin Pore Depends on Channel Width
mBio, 2017 Membrane repair emerges as an innate defense protecting target cells against bacterial pore-forming toxins. Here, we report the first paradigm of Ca2+-dependent repair following attack by a small β-pore-forming toxin, namely, plasmid-encoded phobalysin ...
Gisela von Hoven +7 more
doaj +1 more source
, 2001 Pore-forming bacterial protein toxins: an overview * The cholesterol-dependent cytolysins * Aerolysin from aeromonas hydrophyla and related toxins * Staphylococcal pore-forming toxins * RTX toxin structure and function, a story of numerous anomalies and few analogies in toxin biology * Helicobacter pylori vacuolating cytotoxin: cell intoxication and ...
Menestrina G, Dalla Serra M
+7 more sources
mBio, 2017 Modular bacteriocins represent a major group of secreted protein toxins with a narrow spectrum of activity, involved in interference competition between Gram-negative bacteria.
Maarten G. K. Ghequire +4 more
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The assembly dynamics of the cytolytic pore toxin ClyA [PDF]
, 2015 Pore-forming toxins are protein assemblies used by many organisms to disrupt the membranes of target cells. They are expressed as soluble monomers that assemble spontaneously into multimeric pores.
Nettels, Daniel +11 more
core +1 more source
Host Glycan Recognition by a Pore Forming Toxin [PDF]
Structure, 2012 An exposed F-type lectin domain fused to the N-terminus of a cholesterol-dependent cytolysin scaffold allows Streptococcus mitis lectinolysin to cluster at fucose-rich sites on target cell membranes, thereby leading to increased pore-forming toxin activity.
Bouyain, Samuel, Geisbrecht, Brian V.
openaire +2 more sources
The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States
Membranes, 2021 The electrochemical gradients established across cell membranes are paramount for the execution of biological functions. Besides ion channels, other transporters, such as exogenous pore-forming toxins, may present ionic selectivity upon reconstitution in
Andrew Bogard +6 more
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A biomimetic nanosponge that absorbs pore-forming toxins [PDF]
Nature Nanotechnology, 2013 Detoxification treatments such as toxin-targeted anti-virulence therapy offer ways to cleanse the body of virulence factors that are caused by bacterial infections, venomous injuries and biological weaponry. Because existing detoxification platforms such as antisera, monoclonal antibodies, small-molecule inhibitors and molecularly imprinted polymers ...
Hu, Che-Ming J. +4 more
openaire +2 more sources
Inhibition of Pore-Forming Proteins
Toxins, 2019 Perforation of cellular membranes by pore-forming proteins can affect cell physiology, tissue integrity, or immune response. Since many pore-forming proteins are toxins or highly potent virulence factors, they represent an attractive target for the ...
Neža Omersa +2 more
doaj +1 more source
The Ins and Outs of Anthrax Toxin
Toxins, 2016 Anthrax is a severe, although rather rare, infectious disease that is caused by the Gram-positive, spore-forming bacterium Bacillus anthracis. The infectious form is the spore and the major virulence factors of the bacterium are its poly-γ-D-glutamic ...
Sarah Friebe +2 more
doaj +1 more source
Pore Forming Protein Induced Biomembrane Reorganization and Dynamics: A Focused Review
Frontiers in Molecular Biosciences, 2021 Pore forming proteins are a broad class of pathogenic proteins secreted by organisms as virulence factors due to their ability to form pores on the target cell membrane.
Ilanila Ilangumaran Ponmalar +4 more
doaj +1 more source