Results 81 to 90 of about 18,671,976 (307)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2021 We present a fully coupled pore-network/free-flow model providing pore-scale insight into drying processes. We solve the Navier–Stokes equations with component transport in the free-flow region, coupled to a dynamic two-phase, two-component pore-network ...
Koch, Timo +5 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Image Analysis and Stereology, 2015 A novel methodology is described for porosimetry as well as for water transport through the pore system in dynamic DEM-based virtual cementitious materials.
Kai Li, Piet Stroeven, Nghi LB Le
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A novel pore-fracture dual network modeling method considering dynamic cracking and its applications
Petroleum Research, 2020 Unconventional reservoirs are normally characterized by dual porous media, which has both multi-scale pore and fracture structures, such as low permeability or tight oil reservoirs.
Yukun Chen +7 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Linking sand permeability anisotropy to fabric anisotropy via numerical simulation [PDF]
E3S Web of ConferencesCharacterisation of the permeability of soils is of practical importance and, for cohesionless or granular soils, it can be predicted from the void ratio and the particle size distribution (PSD).
Morimoto Tokio +2 more
doaj +1 more source
Extensive pore modelling (XPM) – a coherent framework for multiscale pore network modelling
It is not uncommon for porous media to span multiple scales of heterogeneity. Geological formations are examples of such complex systems that may act as natural aquifers, hydrocarbon reservoirs or greenhouse gas sequestration units. Application of conventional single scale modelling approaches is not sufficient for representative prediction of flow in ...
Petrovskyy, Dmytro +5 more
openaire +1 more source
Yield stress fluids method to determine the pore size distribution of a porous medium [PDF]
, 2014 In this paper a new method is presented in order to determine the pore size distribution in a porous medium. This original technique uses the rheological properties of some non-Newtonian yield stress fluids flowing through the porous sample.
AMBARI, Abdelhak +2 more
core +1 more source