Results 121 to 130 of about 15,177,396 (356)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A comparative analysis of mercury intrusion and nitrogen adsorption methods for multifractal characterization of shale reservoirs in northern Songliao Basin

Scientific Reports
The northern Songliao Basin is shale-oil-rich with high exploration potential. However, its heterogeneity challenge reservoir characterization and evaluation, impeding exploration and development efforts.
Siyu Chen, Dameng Liu, Yingjin Wang, Weifeng Zhang, Qingwei Zheng, Xinran Yin   +5 more
doaj   +1 more source

Pore structure characterization of low-permeability sandstone by dual LNMR T2 cutoff values: a case study of the fourth member of shahejie formation, dongying sag, jiyang depression

Frontiers in Earth Science
Low-permeability sandstone reservoirs usually exhibit complex pore structure characteristics that significantly controls the type of fluid in the pore space and its occurrence and seepage mechanisms. In this work, the mercury injection capillary pressure
Min Wang, Min Wang, Kang Chen, Bin Geng, Qiang Liang   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The effects of organic farming on the soil physical environment [PDF]

, 2006
The aim of this research was to investigate the effects of organic farming practices on the development of soil physical properties, and in particular, soil structure in comparison with conventional agricultural management.
Bird, N R A, Mooney, S J, Papadopoulos, A, Whitmore, A P   +3 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Micro pore structure characterization and classification evaluation of reservoirs in Weirong Deep Shale Gas Field

Youqicang pingjia yu kaifa, 2021
In order to study the evaluation standard of deep shale reservoirs,their micro pore characteristics have been studied.Based on the ideas of micro pore structure research with "high precision and cross scale",and by using nitrogen adsorption,high pressure
XIONG Liang, PANG Heqing, ZHAO Yong, WEI Limin, ZHOU Hua, CAO Qian   +5 more
doaj