Results 41 to 50 of about 7,489,349 (254)
Applied Sciences, 2022 With the increase of soil consolidation degree, the pore water pressure induced by thermal loading drops dramatically. To conveniently and quickly calculate the thermal pore water pressure inside the soil under different overconsolidation states and ...
Gailei Tian, Zhihong Zhang
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
, 2019 Prediction of the wave-induced instability of seabed due to the build-up of pore water pressure is essential for coastal engineers involved in the foundation design of marine infrastructure.
Cui, HN, Jeng, DS, Zhao, HY, Liu, XL
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Advances in Meteorology, 2015 Knowledge of spatial and temporal variations of soil pore-water pressure in a slope is vital in hydrogeological and hillslope related processes (i.e., slope failure, slope stability analysis, etc.).
M. R. Mustafa +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Data for time-varying pore water pressure
, 2020 Sand conlumn experiments were conducted to describe time-varying pore water pressure. Height of the sand column is fixed as 50 cm and three pore water pressure transducers were deployed along the sidewall of the sand column at 46 cm, 38 cm, 30cm, 22 cm,
yang, M (via Mendeley Data)
core +4 more sources
PRESSURE PREDICTION AND UNDERBALANCED DRILLING IN THE DEEPWATER NIGER DELTA [PDF]
, 2012 The mechanisms that cause overpressure can be broadly classified into two categories: loading and unloading. This study looks at eight wells from the deepwater Niger Delta; the wells were evaluated with three aims in mind. The first aim was to determine
GOODWYNE, OLAR,KAMAL
core