Results 31 to 40 of about 76,766 (266)

Pore-scale numerical simulation of supercritical CO2-brine two-phase flow based on VOF method

Natural Gas Industry B, 2023
CO2 capture and storage technology is favorable for the reduction of CO2 emissions. In recent years, a great number of research achievements have been obtained on CO2 geological storage from nano scale to oil/gas reservoir scale, but most studies only ...
Yongfei Yang, Jinlei Wang, Jianzhong Wang, Qi Zhang, Jun Yao   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Evaluation of a Volume-Averaged Species Transport Model with Micro–Macro Coupling for Breakthrough Curve Prediction

Molecules
In porous water filters, the transport and entrapment of contaminants can be modeled as a classic mass transport problem, which employs the conventional convection–dispersion equation to predict the transport of species existing in trace amounts.
Parham Mobadersani, Naine Tarun Bharat, Krishna M. Pillai   +2 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Sensitivity analysis and economic optimization studies of inverted five-spot gas cycling in gas condensate reservoir

Open Physics, 2017
Gas condensate reservoirs usually exhibit complex flow behaviors because of propagation response of pressure drop from the wellbore into the reservoir.
Shams Bilal, Yao Jun, Zhang Kai, Zhang Lei   +3 more
doaj   +1 more source

Calcification in free-living coralline algae is strongly influenced by morphology: Implications for susceptibility to ocean acidification

Scientific Reports, 2021
Rhodolith beds built by free-living coralline algae are important ecosystems for marine biodiversity and carbonate production. Yet, our mechanistic understanding regarding rhodolith physiology and its drivers is still limited.
Nadine Schubert, Laurie C. Hofmann, Antonella C. Almeida Saá, Anderson Camargo Moreira, Rafael Güntzel Arenhart, Celso Peres Fernandes, Dirk de Beer, Paulo A. Horta, João Silva   +8 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Enclosure enhancement of flight performance

Theoretical and Applied Mechanics Letters, 2014
We use a potential flow solver to investigate the aerodynamic aspects of flapping flights in enclosed spaces. The enclosure effects are simulated by the method of images.
Mehdi Ghommem, Daniel Garcia, Victor M. Calo   +2 more
doaj   +1 more source

Molecular Dynamic Simulation of Crude Oil (SARA) Water Flooding Mechanisms under Different Driving Forces in Oleophilic Pore Channels

Geofluids, 2022
This study investigates the variation of crude oil density distribution with water flooding time for different driving force conditions in the oleophilic pore channel.
Wenguo Ma, Ruilin Ma, Peng Wang
doaj   +1 more source