Results 91 to 100 of about 3,201,741 (356)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Chains in critical fluids and nanopores

open access: yes, 2004
The conformational behavior of a polymer in a critical binary solvent confined in a porous medium is studied. The size of the polymer in bulk, which is mainly governed by the correlation length of the solvent density fluctuations, depends on the ...
Dua, Arti   +2 more
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Laboratory study of cyclic liquid solvent injection process for heavy oil recovery through computed tomography

open access: yesDyna, 2019
The cyclic solvents injection has been considered for years as an improved non-thermal enhanced oil recovery method for the recovery of heavy oil, which includes three stages: injection, soaking, and production.
Maria Isabel Sandoval Martinez   +1 more
doaj   +1 more source

On the global existence and analyticity of the mild solution for the fractional Porous medium equation

open access: yesBoundary Value Problems, 2023
In this research article we focus on the study of existence of global solution for a three-dimensional fractional Porous medium equation. The main objectives of studying the fractional porous medium equation in the corresponding critical function spaces ...
Muhammad Zainul Abidin, Muhammad Marwan
doaj   +1 more source

On non-uniqueness issues related to the permeability of a porous medium with a random porous structure [PDF]

open access: yesarXiv, 2021
This paper discusses the issue of non-uniqueness of the permeability of a porous medium with a random structure. The permeability range for 12,000 realizations of a random porous structure is examined using a recently-developed modelling approach, which results in up to two orders of magnitude permeability variations in low porosities.
arxiv  

Local pore size correlations determine flow distributions in porous media

open access: yes, 2017
The relationship between the microstructure of a porous medium and the observed flow distribution is still a puzzle. We resolve it with an analytical model, where the local correlations between adjacent pores, which determine the distribution of flows ...
Alim, Karen   +3 more
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

On the signed porous medium flow [PDF]

open access: yesNetworks and Heterogeneous Media, 2012
We prove that the signed porous medium equation can be regarded as limit of an optimal transport variational scheme, therefore extending the classical result for positive solutions of [13] and showing that an optimal transport approach is suited even for treating signed densities.
openaire   +1 more source

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