Results 51 to 60 of about 2,863,391 (365)
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
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On the stochastic porous medium equation
Journal of Differential Equations, 2006 The author proves existence and uniqueness for the Cauchy problem and the initial-boundary value problem \[ u_{t}=\sum_{i=1}^{n}\partial_{x_{i}}(| u| ^{p-2}\partial_{x_{i}}u)+\sum_{j=1}^{\infty}f_{j}{dB_{j}\over dt},\quad (t,x)\in (0,T)\times G, \] \(u=0\), \((t,x)\in (0,T)\times\partial G\), \(u(0,x)=u_0(x)\), \(x\in G\), where \(G\) is a bounded ...
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
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A simulation of suspension flow in an artificial porous medium [PDF]
Acta Montanistica Slovaca, 2006 The paper presents research results of a computer simulation of the suspension flow. One of the most difficult problems in petroleum industry is to optimally use different drilling fluids. It is usually a suspension interacting with a porous medium.
Dariusz Knez
doaj
Evaluation of using a porous medium approach to simulate flat-sheet membrane bioreactors
Water Science and Technology, 2022 The porous medium approach has been applied by others to study the global hydrodynamics in hollow-fiber (HF) membrane bioreactors (MBR). This study explores the usability of the porous medium approach for flat-sheet (FS) MBR and introduces a CFD-based ...
Danmei Chen +2 more
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Stability for systems of porous medium type
Journal of Mathematical Analysis and Applications, 2022 We establish stability properties of weak solutions for systems of porous medium type with respect to the exponent $m$. Thereby we treat stability for the local case as well as for Cauchy-Dirichlet problems. Both degenerate and singular cases are covered.
Rainer, Rudolf, Moring, Kristian
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Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
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Journal of Marine Science and Engineering, 2023 Submerged breakwater, as an important marine engineering structure, can effectively absorb wave energy and is widely used in marine engineering protection. As a new type of breakwater, porous medium breakwater has a certain influence on wave propagation.
Kui Zhu +6 more
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
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p-Adic Analogue of the Porous Medium Equation [PDF]
, 2016 We consider a nonlinear evolution equation for complex-valued functions of a real positive time variable and a p-adic spatial variable. This equation is a non-Archimedean counterpart of the fractional porous medium equation. Developing, as a tool, an $$L^
A. Khrennikov, A. Kochubei
semanticscholar +1 more source