Results 111 to 120 of about 495 (140)
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Efficient production of natural sunscreens shinorine, porphyra-334, and mycosporine-2-glycine in Saccharomyces cerevisiae

Metabolic Engineering, 2023
Mycosporine-like amino acids (MAAs) are promising natural sunscreens mainly produced in marine organisms. Until now, metabolic engineering efforts to produce MAAs in heterologous hosts have mainly focused on shinorine production, and the low production levels are still not suitable for industrial applications.
Sojeong Kim   +11 more
openaire   +2 more sources

Porphyra-334, a potential natural source for UVA protective sunscreens

Photochemical & Photobiological Sciences, 2006
The mycosporine-like amino acid (MAA), porphyra-334 (lambda(max) = 334 nm; epsilon = 42,300 M(-1) cm(-1)), was isolated from the aquatic cyanobacterium Aphanizomenon flos-aquae (AFA) and its structure was verified by spectroscopic methods. The UVA absorption properties of the crude methanolic extract were determined against two commercial sun care ...
Avital, Torres   +3 more
openaire   +2 more sources

Unique Structural Relaxations and Molecular Conformations of Porphyra-334 at the Excited State

The Journal of Physical Chemistry B, 2019
Quantum chemistry based simulations were used to examine the excited state of porphyra-334, one of the fundamental mycosporine-like amino acids present in a wide variety of aqueous organisms. Our calculations reveal three characteristic aspects of porphyra-334 related to either its ground or excited state.
Makoto Hatakeyama   +7 more
openaire   +2 more sources

Production of porphyra-334 in transgenic lines of Nannochloropsis salina by the expression of mycosporine-like amino acid biosynthetic genes of P. yezoensis

Journal of Applied Phycology, 2021
Mycosporine-like amino acids (MAAs) are small secondary metabolites produced by some marine species. These compounds absorb ultraviolet (UV) light, typically between 310 and 362 nm, and protect the producers from UV-associated damage. They also have anti-photoaging, anticancer, and anti-inflammatory properties, which has generated considerable interest
Jae-Sun In   +5 more
openaire   +1 more source

The Stereostructure of Porphyra‐334: An Experimental and Calculational NMR Investigation. Evidence for an Efficient ‘Proton Sponge’

Helvetica Chimica Acta, 2007
AbstractThe mycosporine‐like amino acid (MAA) porphyra‐334 (1) is subjected to extensive 1H‐ and 13C‐NMR analysis as well as to density‐functional‐theory (DFT) calculations. All 1H‐ and 13C‐NMR signals of 1 are assigned, as well as the resonances of prochiral proton pairs.
Manfred Klisch   +4 more
openaire   +1 more source

The deactivation pathways of the excited-states of the mycosporine-like amino acids shinorine and porphyra-334 in aqueous solution

Photochemical & Photobiological Sciences, 2004
In vitro studies on the structurally related mycosporine-like amino acids (MAAs) porphyra-334 and shinorine in aqueous solutions were carried out aiming at their full photochemical and photophysical characterization and expanding the evidence on the assigned UV-photoprotective role of the molecules in vivo. The experiments on shinorine confirmed a high
Federico R, Conde   +2 more
openaire   +2 more sources

The photoprotector mechanism of mycosporine-like amino acids. Excited-state properties and photostability of porphyra-334 in aqueous solution

Journal of Photochemistry and Photobiology B: Biology, 2000
The photostability and photophysical parameters of an aqueous solution of the mycosporine-like amino acid (MAA) porphyra-334 have been determined. The excited-singlet state lifetime, measured by time-correlated single photon counting, was 0.4 ns. Laser flash photolysis experiments at 355 nm did not show any transient species.
F R, Conde, M S, Churio, C M, Previtali
openaire   +2 more sources

Production of new antioxidant compound from mycosporine-like amino acid, porphyra-334 by heat treatment

Food Chemistry, 2009
Abstract In this study, we evaluated the antioxidant activity (diphenylpicrylhydrazyl (DPPH)-radical scavenging activity) of the low-molecular weight fraction of water-soluble Susabinori ( Porphyra yezoensis ) extract (LMF). DPPH-radical scavenging activity of LMF (65.5 μmol-Trolox eq/ml) was enhanced at temperatures over 100 °C (1.4, 2.0 and 2.4 ...
Masahiro Yoshiki   +7 more
openaire   +1 more source

Novel glycosylated mycosporine-like amino acid, 13-O-(β-galactosyl)-porphyra-334, from the edible cyanobacterium Nostoc sphaericum-protective activity on human keratinocytes from UV light

Journal of Photochemistry and Photobiology B: Biology, 2017
A UV-absorbing compound was purified and identified as a novel glycosylated mycosporine-like amino acid (MAA), 13-O-β-galactosyl-porphyra-334 (β-Gal-P334) from the edible cyanobacterium Nostoc sphaericum, known as "ge xian mi" in China and "cushuro" in Peru. Occurrence of the hexosylated derivative of shinorine (hexosyl-shinorine) was also supported by
Kenji Ishihara   +9 more
openaire   +2 more sources

Comparative functional evaluation of the atypically modified GlcHMS326 and porphyra-334, Two structurally distinct mycosporine-like amino acids

Bioscience, Biotechnology, and Biochemistry
Abstract Mycosporine-like amino acids (MAAs) are natural compounds widely studied for their photoprotective and antioxidant properties. Typical MAAs consist of one or two amino acids attached to a cyclohexenone or cyclohexenimine ring, whereas atypical MAAs possess unique chemical modifications such as glycosylation and methylation ...
Taiki Aono   +5 more
openaire   +2 more sources

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