Results 121 to 130 of about 11,286 (212)

High Prevalence of Insulin Resistance in Asymptomatic Patients with Acute Intermittent Porphyria and Liver-Targeted Insulin as a Novel Therapeutic Approach [PDF]

open access: gold, 2021
Isabel Solares   +11 more
openalex   +1 more source

Evaluation of Metabolic Changes in Acute Intermittent Porphyria Patients by Targeted Metabolomics [PDF]

open access: gold, 2022
Àlex Gomez‐Gómez   +7 more
openalex   +1 more source

Cytosolic persistence of mouse brain CYP1A1 in chronic heme deficiency [PDF]

open access: yes, 2017
Previous work has demonstrated that the function of extrahepatic cytochrome P450 CYP1A1 is dependent on the availability of heme. CYP1A1 is involved in the activation of polyaromatic hydrocarbons.
Hoffmann, Francine   +3 more
core  

04185 The good, the bad and the ugly: glucose, insulin and heme deficiency – impairment of glucose metabolism in patients with acute hepatic porphyrias presenting with recurrent attacks [PDF]

open access: gold
Amadeu Queiroz   +6 more
openalex   +1 more source

Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria

open access: green, 2018
Pedro Urquiza   +26 more
openalex   +2 more sources

Use of Di- and Tripropionate substrate analogs to probe the active site of human recombinant coproporphyrinogen oxidase [PDF]

open access: yes, 2008
Background: Defects in the enzyme coproporphyrinogen oxidase result in accumulation of porphyrins which may affect the severity of a subset of porphyrias. Thus evaluation of this enzyme for substrate selectivity is of value.
Barto, Reyna L   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy