Results 101 to 110 of about 17,878 (259)

Cutaneous Porphyrias: Causes, Symptoms, Treatments and the Danish Incidence 1989-2013.

Acta Dermato-Venereologica, 2016
Porphyrias are rare diseases caused by altered haem synthesis leading to the accumulation of different haem intermediates. Neurovisceral attacks may occur in acute porphyrias, while photosensitivity is the presenting symptom in cutaneous porphyrias.
Anne L. Christiansen, L. Aagaard, A. Krag, L. Rasmussen, A. Bygum   +4 more
semanticscholar   +1 more source

Serum organochlorines and urinary porphyrin pattern in a population highly exposed to hexachlorobenzene [PDF]

, 2002
Background: Porphyria cutanea tarda (PCT) is caused by hexachlorobenzene (HCB) in several species of laboratory mammals, but the human evidence is contradictory.
Jordi Sunyer, Carmen Herrero, Dolores Ozalla, Maria Sala, Núria Ribas-Fitó, Joan Grimalt, Xavier Basagaña, RK Ockner, H Peters, I Dogramaci, I Dogramaci, ES Mazzei, A Morley, JE Burns, MF Currier, JO Grimalt, M Sala, C Herrero, JL Santos, WE Daniell, M Sala, J To-Figueras, E Rossi, GH Elder, D Ozalla, E Rocchi, JE Burns, A Sélden, RE Jones, GM Calvert, D Jung, G García-Vargas, JS Woods, GYH Lyp, PR Sinclair, APJM van Birgelen   +35 more
core   +1 more source

Determination of Dental Lesions in Dairy Cattle and Immunochemical Detection of the Biomarker Decorin in Gingival Crevicular Fluid of Dairy Cattle

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
This study identified dental and gingival lesions in dairy cattle, revealing the significance of routine periodontal assessment for animal welfare. Decorin levels in GCF samples were compared between healthy and diseased cattle, indicating its potential as a non‐invasive biomarker for dental inflammation.
Nihan AVCI
wiley   +1 more source

Photosensitivity Skin Disorders in Childhood [PDF]

, 2010
Photosensitivity in childhood is caused by a diverse group of diseases. A specific sensitivity of a child’s skin to ultraviolet light is often the first manifestation or a clinical symptom of photodermatosis.
Ines Sjerobabski-Masnec, Lena Kotrulja, Mirna Šitum, Sanja Poduje, Suzana Ožanić-Bulić   +4 more
core   +1 more source

Preclinical Development of a Subcutaneous ALAS1 RNAi Therapeutic for Treatment of Hepatic Porphyrias Using Circulating RNA Quantification

Molecular Therapy: Nucleic Acids, 2015
The acute hepatic porphyrias are caused by inherited enzymatic deficiencies in the heme biosynthesis pathway. Induction of the first enzyme 5-aminolevulinic acid synthase 1 (ALAS1) by triggers such as fasting or drug exposure can lead to accumulation of ...
Amy Chan, A. Liebow, Makiko Yasuda, Lin Gan, T. Racie, Martin E. Maier, S. Kuchimanchi, Donald J. Foster, S. Milstein, K. Charissé, A. Sehgal, M. Manoharan, R. Meyers, K. Fitzgerald, A. Simon, R. Desnick, W. Querbes   +16 more
semanticscholar   +1 more source

Exacerbation of erythropoietic protoporphyria by hyperthyroidism [PDF]

, 2018
Erythropoietic protoporphyria (EPP) is a hereditary disorder caused by deficiency of ferrochelatase, the last enzyme in the heme biosynthetic pathway. The majority of EPP patients present with a clinical symptom of painful phototoxicity.
Haldemann, Andreas, Minder, Elisabeth, Schneider-Yin, Xiaoye   +2 more
core  

The Porphyrias

Dermatologic Clinics, 1987
The porphyrias are a group of disorders of heme metabolism that result from partial defects in the several enzymes that control heme biosynthesis. Accumulation of porphyrins or porphyrin precursors in several different patterns results from these defects and biochemically characterizes each specific syndrome.
openaire   +2 more sources

Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell InjurySummary

Cellular and Molecular Gastroenterology and Hepatology, 2019
Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinoma ...
Dhiman Maitra, Juliana Bragazzi Cunha, Jared S. Elenbaas, Herbert L. Bonkovsky, Jordan A. Shavit, M. Bishr Omary   +5 more
doaj   +1 more source

La porfiria aguda intermitente y el cirujano: un reto diagnóstico Reporte de un caso y revisión de la literatura Acute intermittent porphyria and the surgeon: a diagnostic challenge. Case report and literature review

Revista Colombiana de Cirugía, 2011
La porfiria intermitente aguda es conocida, en el ámbito de la cirugía, como una de las causas de abdomen agudo no quirúrgico. No obstante, lo que no se menciona con frecuencia es la posibilidad de que cualquier procedimiento quirúrgico precipite un ...
Lilian Torregrosa, Juan Carlos Ayala, Sergio Cervera, Carlos Andrés Villa   +3 more
doaj  

Oxidative stress, Nrf2 and keratin up‐regulation associate with Mallory‐Denk body formation in mouse erythropoietic protoporphyria [PDF]

, 2012
Mallory‐Denk bodies (MDBs) are hepatocyte inclusions commonly seen in steatohepatitis. They are induced in mice by feeding 3,5‐diethoxycarbonyl‐1,4‐dihydrocollidine (DDC) for 12 weeks, which also causes porphyrin accumulation.
Abou-Sleiman, Andersen, Askanas, Bardag-Gorce, Bloomer, Casanova-Gonzalez, Davies, Endo, Fontanellas, Hanada, Hanada, Harada, Inami, Kerns, Klaassen, Koningsberger, Ku, Libbrecht, Lyoumi, Magin, Magness, Matilla, McGuire, Mohanty, Nakamichi, Puy, Rakoski, Rufenacht, Snider, Strnad, Tangeras, Tao, Tutois, Whalen, Zatloukal   +34 more
core   +1 more source