Results 81 to 90 of about 17,878 (259)
Skin Fragility and Hyperpigmentation in a Patient With HIV
JEADV Clinical Practice, EarlyView.
Catalina Retamal +2 more
wiley +1 more source
Epilepsy: Molecular Pathogenesis and Emerging Therapies
MedComm, Volume 7, Issue 4, April 2026.Progress has been made in the molecular pathogenesis of epilepsy, revealing multiple therapeutic targets. Recent advances in pharmacology, materials science, and surgical technique, coupled with progress in targeted therapy and disruptive epilepsy network technology, have led to the emergence of innovative strategies for epilepsy treatment.
Wanbin Huang +5 more
wiley +1 more source
Molecular Genetics and Metabolism, 2019 Mouse models of the human porphyrias have proven useful for investigations of disease pathogenesis and to facilitate the development of new therapeutic approaches.
Makiko Yasuda, R. Desnick
semanticscholar +1 more source
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink +9 more
wiley +1 more source
Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes [PDF]
, 2011 Extracellular matrix alterations are important elements in the arterial changes seen in diabetes, being associated with increased vascular stiffness and the development of cardiovascular diseases.
Aagard, Jan +16 more
core +1 more source
The Case of a 37‐Year‐Old Woman Presenting With Subacute Weakness and Paresthesias
Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 639-640, March 2026.ABSTRACT Acute intermittent porphyria (AIP) is a rare metabolic disorder that may present with subacute neuropathy and systemic symptoms, often leading to diagnostic delay. We report a 37‐year‐old woman with eight weeks of progressive bilateral upper extremity weakness and paresthesias, followed by lower extremity involvement and falls, in the setting ...
Peter Pacut +3 more
wiley +1 more source
Presentations associated with porphyrias in intensive care units
Southwest Respiratory and Critical Care Chronicles, 2016 Porphyrias are a group of uncommon congenital metabolic diseases that are difficult to diagnose as they often present with nonspecific symptoms, mimicking other diseases.
Doungporn Ruthirago +2 more
doaj
Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]
, 2018 INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo +5 more
core +1 more source
Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
Advanced Materials, Volume 38, Issue 17, 20 March 2026.RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
Acute Intermittent Porphyria in a Man with Dual Enzyme Deficiencies
Case Reports in Genetics, 2020 Porphyrias are a heterogeneous group of metabolic disorders that result from the altered activity of specific enzymes of the heme biosynthetic pathway and are characterized by accumulation of pathway intermediates.
G. N. Cerbino +6 more
doaj +1 more source