Results 71 to 80 of about 3,279 (202)

Remibrutinib as a Therapeutic Option for Solar Urticaria

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 6, November 2026.
Joshua Mijares, Manoj Bhagwat, Johanna Gonzalez, Vignesh Ramachandran   +3 more
wiley   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 747-756, August 2026.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil, Polyxeni Delaporta, Konstantinos Bistas, Antonis Kattamis   +3 more
wiley   +1 more source

Xenobiotics Triggering Acute Intermittent Porphyria and Their Effect on Mouse Brain Respiratory Complexes

Journal of Xenobiotics
Heme enzyme dysfunction causes a group of diseases called porphyrias. Particularly, a decrease in porphobilinogen deaminase, involved in the third step of heme biosynthesis, leads to acute intermittent porphyria (AIP).
Johanna Romina Zuccoli, María del Carmen Martínez, Pablo Vallecorsa, Ana María Buzaleh   +3 more
doaj   +1 more source

Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell InjurySummary

Cellular and Molecular Gastroenterology and Hepatology, 2019
Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinoma ...
Dhiman Maitra, Juliana Bragazzi Cunha, Jared S. Elenbaas, Herbert L. Bonkovsky, Jordan A. Shavit, M. Bishr Omary   +5 more
doaj   +1 more source

Porphyrias: clinical presentation, diagnosis and treatment

, 2010
As porfirias são doenças incomuns e de herança genética na maior parte dos casos. As porfirias são divididas em eritropoiéticas, hepáticas agudas e hepáticas crônicas.
Dinardo, Carla Luana, Gualandro, Sandra Fátima Menosi, Chamone, Dalton de Alencar Fischer, Fonseca, Guilherme Henrique Hencklain, Suganuma, Liliana Mitie   +4 more
core   +1 more source

La porfiria aguda intermitente y el cirujano: un reto diagnóstico Reporte de un caso y revisión de la literatura Acute intermittent porphyria and the surgeon: a diagnostic challenge. Case report and literature review

Revista Colombiana de Cirugía, 2011
La porfiria intermitente aguda es conocida, en el ámbito de la cirugía, como una de las causas de abdomen agudo no quirúrgico. No obstante, lo que no se menciona con frecuencia es la posibilidad de que cualquier procedimiento quirúrgico precipite un ...
Lilian Torregrosa, Juan Carlos Ayala, Sergio Cervera, Carlos Andrés Villa   +3 more
doaj  

Letter to the Editor—Comment on “Erythropoietic Protoporphyria and Surgery: A Case of Successful Mastectomy With Perioperative Light Shielding Strategies Based on Light‐Induced Hemolytic Threshold Assessment”

The Journal of Dermatology, Volume 53, Issue 9, Page e767-e768, September 2026.
Ingeborg de Rover, N. Chantal Peltenburg, Johan C. M. Sweep, Janneke G. Langendonk   +3 more
wiley   +1 more source

Diagnostic Dilemmas in Hepatitis C Virus Infection for Hemodialysis Patients

Folia Medica, 2017
Background: Hepatitis C virus (HCV) is a leading cause of chronic hepatitis in dialysis patients. The diagnosis of HCV infection in these patients is predominantly based on laboratory tests because of the specificity of the clinical course of the disease.
Komitova Radka T., Atanasova Maria V., Pavlova Toska A., Nyagolov Monica Sh., Ivanova Aneta V.   +4 more
doaj   +1 more source

Microelements and Inherited Metabolic Diseases

Acta Medica, 2002
In addition to the main groups of inherited metabolic diseases, including mitochondrial, peroxisomal and lysosomal defects, organic acidurias, porphyrias, defects of amino acids, saccharides and fatty acids metabolism, disorders of transport and ...
Eliška Marklová
doaj   +1 more source