Results 91 to 100 of about 35,118 (303)

Inhibition of osteoclastogenesis by opsonized Porphyromonas gingivalis [PDF]

FASEB BioAdvances, 2019
Abstract A crucial step in the pathogenesis of periodontal disease (PD) is activation of osteoclasts (OC) by numerous virulence factors produced by Porphyromonas gingivalis ( Pg ).
Pandruvada, Subramanya N., Ebersole, Jeffrey L., Huja, Sarandeep S.   +2 more
openaire   +2 more sources

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Porphyromonas gingivalis induces vascular cells expression of Egr-1 and Cyr61 in atherosclerosis [PDF]

, 2010
根據行政院衛生署統計民國96年國人十大死因，心臟疾病與腦血管疾病分別位居第二及第三名，嚴重威脅國人健康。近年研究顯示細菌感染可能是血管發生病變的原因之一，其中牙周病亦與心血管疾病具密切相關性。 Porphyromonas gingivalis (P.g.)是造成牙周病的致病菌之一，文獻指出P.g.會隨血液在血管裡流動，出現在動脈硬化發生的區域。 最近研究發現，粥狀動脈硬化斑塊處有大量的Cyr61及Egr-1表現。Cyr61表現量的多寡與動脈硬化惡化程度呈正比，Cyr61及Egr-1 ...
Wang, Hsi-Wen, 王希文
core  

Benzamidine derivatives inhibit the virulence of Porphyromonas gingivalis [PDF]

, 2013
We have previously shown that benzamidine-type compounds can inhibit the activity of arginine-specific cysteine proteinases (gingipains HRgpA and RgpB); well-known virulence factors of Porphyromonas gingivalis.
Plaza, Karolina, Potempa, Jan, Pfister, W., Schmidt, Karl-Hermann, Fröhlich, Esther, Kantyka, Tomasz, Pfister, Wolfgang, Plaza, K., Eick, S., Schmidt, K. H., Eick, Sigrun, Froehlich, E.   +11 more
core   +1 more source

In vitro study of 980nm diode laser in dental implant disinfection [PDF]

RGO: Revista Gaúcha de Odontologia, 2009
Objective: To evaluate the potential of 980nm diode laser to reduce bacteria after irradiation of three different dental implant surfaces contaminated with Enterococcus faecalis and Porphyromonas gingivalis, as well as the possible changes in the ...
Fábio Gonçalves, Artêmio Luiz Zanetti, Raquel Virgínia Zanetti, Saturnino Aparecido Ramalho   +3 more
doaj  

Genetic exchange and reassignment in Porphyromonas gingivalis [PDF]

Journal of Oral Microbiology, 2018
Porphyromonas gingivalis is considered a keystone pathogen in adult periodontitis but has also been associated with systemic diseases. It has a myriad of virulence factors that differ between strains. Genetic exchange and intracellular genome rearrangements may be responsible for the variability in the virulence of P. gingivalis.
Olsen, Ingar, Chen, Tsute, Tribble, Gena D   +2 more
openaire   +5 more sources

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

KEMAMPUAN IMMUNOGLOBULIN Y Porphyromonas gingivalis TERHADAP DAYA ADERENSI BAKTERI Porphyromonas gingivalis DAN Fusobacterium nucleatum [PDF]

, 2018
Bakteri Porphyromonas gingivalis merupakan bakteri utama penyebab penyakit periodontitis kronis. Selain Porphyromonas gingivalis, terdapat bakteri Fusobacterium nucleatum yang juga merupakan bakteri penyebab periodontitis kronis.
NOVA ANDRIANI HEPITARIA, 021511133127
core  

Comparative gene expression analysis of Porphyromonas gingivalis ATCC 33277 in planktonic and biofilms states [PDF]

, 2017
Background and objective Porphyromonas gingivalis is a keystone pathogen in the onset and progression of periodontitis. Its pathogenicity has been related to its presence and survival within the subgingival biofilm.
Romero Lastra, Patricia, Sanz Alonso, Mariano, Llama Palacios, María Arantxazu, Ribeiro Vidal, Honorato, Figuero Ruiz, Elena, Sánchez Beltrán, María Del Carmen, Herrera González, David   +6 more
core   +1 more source