Results 41 to 50 of about 10,981,272 (272)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Adverse-Pressure-Gradient effects on Turbulent Boundary Layers [PDF]

, 2018
Wall-bounded turbulence is present in many relevant fluid-flow problems such as the flow around wings, land and sea vehicles, or in turbines, compressors, etc. Simplified scenarios, such as the zero-pressure-gradient (ZPG) turbulent boundary layers (TBL)
Discetti, Stefano
core  

The resilience of the logarithmic law to pressure gradients: evidence from direct numerical simulation [PDF]

, 2009
Wall-bounded turbulence in pressure gradients is studied using direct numerical simulation (DNS) of a Couette–Poiseuille flow. The motivation is to include adverse pressure gradients, to complement the favourable ones present in the well-studied ...
Johnstone, Roderick, Coleman, Gary N., Spalart, Philippe R.   +2 more
core   +1 more source

Supporting AI Readiness Through Digital Workflows in Materials Science

Advanced Engineering Materials, EarlyView.
Digitalization drives innovation in materials science by connecting data silos and turning heterogeneous processes into reusable research pipelines. Across 13 MaterialDigital projects, digital workflows reveal complementary pathways toward AI‐ready materials research, founded on structured data, persistent artifacts, executable orchestration, and ...
Marian Bruns, Lateef Abdul, Stephan Barth, Martin Glauer, Manuel Günther, Fabian Neuhaus, Jan‐Ole Perschewski, Thomas Bjarsch, Henrik Abel, Johannes Bosch, Niklas Meyer, Peter Hofmann, Marc Drechsler, Alexander Dyck, Dhanunjaya Kumar Nerella, Marvin Tegeler, Oleg Shchyglo, Ingo Steinbach, Timo Klecker, Henk Birkholz, Ehsan Borzabadi Farahani, Bernard Fedelich, Cetin Haftaoglu, Tarakeshwar Lakshmipathy, Elena Garcia Trelles, Christoph Schweizer, Reza Darvishi Kamachali, Lukas Koschmieder, Janin Eiken, Markus Apel, Sung‐Min Wi, Jiangdong Zhao, Andreas Fezer, Nicolas Christ, Patrick Schneider, Eldor Urinov, Veit Königer, Volker Knoblauch, Janik Harter, Thomas Seifert, Thitichai Janpheng, Florian Fuchs, Fabian Teichert, Jörg Schuster, Anke Bardehle, Andreas Limper, Ulrich Giese, Carlos Lucke, Mario Beiner, Christoph Gögelein, Lisa Leuchtenberger‐Engel, Christian Hopmann, Felix Wentzien, Heike Wittek, Benjamin Klie, Alexander Röhrs, Ludger Overmeyer, Achraf Atila, Marcel Sadowski, Leopold Talirz, Jan Janssen, Jesper R. Pedersen, Peter Beck, Tejs Vegge, Ivano E. Castelli, Wolfgang Wenzel, Tilmann Hickel, Jörg Schaarschmidt   +67 more
wiley   +1 more source

Impact of transjugular intrahepatic portosystemic shunt creation on the central lymphatic system in liver cirrhosis

Scientific Reports, 2021
The puropse of this study was to evaluate associations of cisterna chyli (CCh) diameter with portal hemodynamics and the influence of TIPS-creation in cirrhotic patients.
Claus Christian Pieper, Andreas Feißt, Carsten Meyer, Julian Luetkens, Michael Praktiknjo, Jonel Trebicka, Ulrike Attenberger, Christian Jansen   +7 more
doaj   +1 more source

A Predictive Formula for Portal Venous Pressure Prior to Liver Resection Using Directly Measured Values [PDF]

, 2018
Purpose: Despite refinements in surgical techniques for liver resection, evaluation of hepatic reserve disparity remains one of the most common problems in liver surgery, especially for hepatic malignancies such as hepatocellular carcinoma (HCC).
Takanobu Hara, Adachi, Tomohiko, Takatsuki, Mitsuhisa, Masaaki Hidaka, Hara, Takanobu, Okada, Satomi, Akihiko Soyama, Susumu Eguchi, Kanetaka, Kengo, Mitsuhisa Takatsuki, Kengo Kanetaka, Satomi Okada, Ono, Shinichiro, Takashi Hamada, Hidaka, Masaaki, Soyama, Akihiko, Shinichiro Ono, Tomohiko Adachi, Eguchi, Susumu, Hamada, Takashi   +19 more
core   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS

Hepatology, EarlyView., 2022
The river diagram demonstrates that after transjugular intrahepatic portosystemic shunt insertion (TIPS) the majority of patients without ascites and 50% of the patients with ascites detectable at ultrasound, show the best response in the long term follow‐up.
Alexander Queck, Louise Schwierz, Wenyi Gu, Philip G. Ferstl, Christian Jansen, Frank E. Uschner, Michael Praktiknjo, Johannes Chang, Maximilian J. Brol, Filippo Schepis, Manuela Merli, Christian P. Strassburg, Jennifer Lehmann, Carsten Meyer, Jonel Trebicka   +14 more
wiley   +1 more source

Endoscopic ultrasound‐guided portal pressure gradient identifies patients with previously undiagnosed clinically significant portal hypertension

Portal Hypertension & Cirrhosis
Aims Portal hypertension (PH) is a complication of cirrhosis that leads to hepatic decompensation. Assessing the portal pressure gradient (PPG) provides valuable information for disease assessment, staging, and prognosis.
Jerome C. Edelson, Scott F. D. Edelson, John G. Quiles, Cyrus V. Edelson, Eric M. Montminy, Christian L. Horn, John P. Magulick, Don C. Rockey   +7 more
doaj   +1 more source

Preliminary clinical observation of double C-arm digital subtraction angiography guidance during transjugular intrahepatic portosystemic shunt placement

BMC Gastroenterology, 2023
Background This study aimed to investigate the safety, preliminary clinical experience, and technical advantages of double C-arm digital subtraction angiography -assisted portal vein puncture for transjugular intrahepatic portosystemic shunt.
Jianqiao Chen, Xiao Bai, Chunyan Wang, Jihua Li, Weiguo Xu   +4 more
doaj   +1 more source