Results 61 to 70 of about 10,981,272 (272)

Persistent varices in cured patients: Understanding the role of hepatic venous pressure gradient

JHEP Reports
Background & Aims: Etiologic factor removal (ER) drives recompensation and improves portal hypertension in cirrhosis. Esophageal varices (EV) and portosystemic shunts (PSS) have been found in patients despite hepatic venous pressure gradient (HVPG ...
Pol Olivas, Alexandre Soler-Perromat, Luis Tellez, José Antonio Carrión, Edilmar Alvarado-Tapias, José Ferrusquía-Acosta, Sabela Lens, Antonio Guerrero, Ángeles Falgà, Pamela Vizcarra, Lara Orts, Valeria Perez-Campuzano, Sarah Shalaby, Sonia Torres, Anna Baiges, Fanny Turon, Juan Carlos García-Pagán, Ángeles García-Criado, Virginia Hernández-Gea   +18 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Splenic vein stenting for recurrent chylous ascites in sinistral portal hypertension: a case report

CVIR Endovascular, 2021
Background Sinistral portal hypertension results from obstruction or stenosis of the splenic vein and is characterized by normal portal vein pressures and liver function tests.
Brian Covello, Jacob Miller, Roberto Fourzali   +2 more
doaj   +1 more source

Endoscopic ultrasound guided portal pressure gradient measurement [PDF]

, 2019
Portal hypertension is most commonly associated as a complication related to liver cirrhosis. Portal hypertension increases morbidity and mortality usually through gastrointestinal bleeding however other complications such as ascites formation and subsequent spontaneous bacterial peritonitis may occur.
openaire   +3 more sources

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

Advanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng, Masaki Nasu, Ayman Abdul‐Ghani, Yu Chen, Shaoqiu Chen, Isam Mohd Ibrahim, Hanqiu Zhang, Lauren Higa, Zitong Gao, Hua Yang, Raphael Bueno, Loïc Le Marchand, Youping Deng   +12 more
wiley   +1 more source

Hepatic venous pressure gradient measurement in pre-primary and primary prophylaxis of variceal hemorrhage

Annals of Hepatology, 2013
Pharmacological therapy of portal hypertensi¢n can be accomplished according to different objectives. Among them, pre-primary prophylaxis aims to avoid / delay esophageal varices development while the target of primary prophylaxis is protection against ...
Julio D. Vorobioff, M.D., Roberto J Groszmann   +1 more
doaj   +1 more source

Hepatic Venous Pressure Gradient: Measurement and Pitfalls. [PDF]

Measurement of hepatic venous pressure gradient (HVPG) effectively mirrors the severity of portal hypertension (PH) and offers valuable insights into prognosis of liver disease, including the risk of decompensation and mortality.
Berzigotti, Annalisa, Delgado, Maria Gabriela, Stirnimann, Guido, Bosch, Jaime, G Rodrigues, Susana   +4 more
core   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Comparison of artificial neural network-predicted PPG and HVPG with measured PPG in decompensated cirrhosis patients

Scientific Reports
Portal hypertension (PHT) is pivotal in managing decompensated cirrhosis. In clinical practice, hepatic venous collaterals are frequently present, often leading to failure or reduced accuracy of hepatic venous pressure gradient (HVPG) measurements ...
Zhonghua Wang, Ziwen Liu, Mengxin Lv, Yulin Wang, Yuanzi Yu, Tao Li, Jinhua Hu   +6 more
doaj   +1 more source

Change in Portal Pressure and Clinical Outcome in Cirrhotic Patients with Gastric Varices after Plug-Assisted Retrograde Transvenous Obliteration

Gut and Liver, 2020
Background/Aims: Plug-assisted retrograde transvenous obliteration (PARTO) is widely used to manage gastric varices with a portosystemic shunt. It is not clear whether portal pressure and the incidence of complications increase after PARTO.
Jae Woo Park, Jeong-Ju Yoo, Sang Gyune Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Jae Myung Lee, Jong Joon Shim, Young Don Kim, Gab Jin Cheon, Baek Gyu Jun, Young Seok Kim   +12 more
doaj   +1 more source