Results 81 to 90 of about 10,981,272 (272)

Agreement of endoscopic ultrasound–guided portal pressure gradient with hepatic venous pressure gradient for portal hypertension severity classification: a systematic review and meta-analysis

The Egyptian Journal of Internal Medicine
Background The severity of portal hypertension (PH) is central to risk stratification in chronic liver disease, yet transjugular HVPG testing is resource-intensive.
Mahnoor Afridi, Wajahat Mirza, Imtiaz Alam Afridi, Sadia Tarar, Syed Shujah Ul Hassan, Iqra Yaqoob, Abdullah Imtiaz, Maaz Bin Badshah   +7 more
doaj   +1 more source

EUS-guided portal pressure gradient measurement: a promising tool in noncirrhotic portal hypertension [PDF]

Gastrointestinal Endoscopy, 2021
Hangfei, Xu, Huiguo, Ding
openaire   +2 more sources

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Hepatic venous pressure gradient measurement in clinical hepatology.

, 2011
Portal hypertension is key to the natural history of cirrhosis and the standard way to assess it is the hepatic venous pressure gradient. Hepatic venous pressure gradient is a strong predictor of variceal bleeding/survival and is the only suitable tool ...
Sara Montagnese, MONTAGNESE, SARA, MERKEL, CARLO, Carlo Merkel   +3 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Serum levels of BSP significantly correlated to markers for portal pressure.

, 2020
BSP serum levels were correlated to different laboratory parameters routinely assessed in patients with liver cirrhosis as well as with markers for portal pressure including portal pressure before TIPS, portal hepatic pressure gradient after TIPS and ...
Michael Praktiknjo (4854148), Sven Loosen (3443141), Alexander Wree (668904), Muenevver Demir (8727165), Fabian Benz (2636641), Andreas Bogen (8727162), Robert Schierwagen (605493), Frank Tacke (170575), Christian Jansen (605490), Mihael Vucur (180119), Jonel Trebicka (206006), Christoph Roderburg (180091), Carsten Meyer (4854151)   +12 more
core   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Portosystemic shunt for variceal esophagogastric bleeding and risk of early re-bleeding. Rationale for involuntary intervention: A single-center observational controlled study

Кубанский научный медицинский вестник
Background. Variceal esophageal-gastric bleeding is considered to be a life-threatening complication of portal hypertension in patients with cirrhosis.
Yu. V. Khoronko, E. V. Kosovtsev, R. V. Korobka, A. E. Sarkisov, E. Yu. Khoronko, I. A. Ashimov, E. V. Tadieva   +6 more
doaj   +1 more source

Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model

Advanced Science, EarlyView.
Longitudinal multifrequency magnetic resonance elastography (mMRE) performed on a clinical 3 Tesla magnetic resonance imaging system reveals early biomechanical alterations during liver tumor progression in a translational VX2 model. Changes in tumor stiffness and viscosity precede diffusion‐related alterations and are associated with extracellular ...
Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A. S. Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N. Müller, Ingolf Sack, Jing Guo, Shraga Nahum Goldberg, Lynn Jeanette Savic   +20 more
wiley   +1 more source

A Case of Ileal Conduit Bleeding Caused by Porto‐Sinusoidal Vascular Disorder

Portal Hypertension & Cirrhosis
A 60‐year‐old man presented with recurrent stomal bleeding for 3 years. He had undergone cystoprostatectomy with ileal conduit diversion for bladder cancer 7 years prior. Endoscopy revealed multiple protruding lesions (0.6–0.8 cm) inside the stoma, which
Lu Yu, Hao Wu, Huan Tong
doaj   +1 more source