Results 61 to 70 of about 976,374 (357)

Evaluation of sorafenib in Chinese unresectable hepatocellular carcinoma patients with prior surgery and portal vein tumor thrombosis: A subset analysis of GIDEON study data

open access: yesTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017
The purpose of this study was to examine the safety and efficacy of sorafenib in Chinese patients with unresectable hepatocellular carcinoma. Data of 338 Chinese patients from the Global Investigation of therapeutic DEcisions in hepatocellular carcinoma ...
S. Ye   +10 more
semanticscholar   +1 more source

Engineering Volumetric Tissue Analogs via Assembly of Endothelial Cell‐Covered Spheroidal Microtissues

open access: yesAdvanced Healthcare Materials, EarlyView.
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh   +5 more
wiley   +1 more source

Microsurgical Technique of Simultaneous Pancreas/Kidney Transplantation in the Rat: Clinical Experience and Review of the Literature [PDF]

open access: yes, 2009
Background: For experimental basic research, standardized transplantation models reflecting technical and immunologic aspects are necessary. This article describes an experimental model of combined pancreas/kidney transplantation (PKTx) in detail ...
Bald, C.   +8 more
core   +1 more source

Management of hepatocellular carcinoma with portal vein tumor thrombosis: Review and update at 2016.

open access: yesWorld Journal of Gastroenterology, 2016
Portal vein tumor thrombosis (PVTT) is a common phenomenon in hepatocellular carcinoma (HCC). Compared to HCC without PVTT, HCC with PVTT is characterized by an aggressive disease course, worse hepatic function, a higher chance of complications related ...
S. Chan   +4 more
semanticscholar   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

open access: yesAdvanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor   +12 more
wiley   +1 more source

Transarterial chemoembolization (TACE) combined with sorafenib versus TACE for hepatocellular carcinoma with portal vein tumor thrombus: a systematic review and meta-analysis

open access: yesOncoTarget, 2017
Background The benefits of transarterial chemoembolization plus sorafenib (TACE-S) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) remain controversial.
Xiuping Zhang   +6 more
semanticscholar   +1 more source

Mechanochemistry for Metal–Organic Frameworks and Covalent–Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

open access: yesAdvanced Materials, EarlyView.
An overview is provided of the mechanochemistry of metal‐organic frameworks (MOFs) and covalent‐organic frameworks (COFs), highlighting opportunities and strategies for discovery, synthesis and reactivity studies of these materials. Mechanistic studies and comparisons to the mechanochemistry of organic solids are outlined, showcasing how advances in ...
Joseph M. Marrett   +3 more
wiley   +1 more source

Portal Revascularization in the Setting of Cavernous Transformation Through a Paracholedocal Vein: A Case Report [PDF]

open access: yes, 2010
Diffuse thrombosis of the entire portal system (PVT) and cavernomatous transformation of the portal vein (CTPV) represents a demanding challenge in liver transplantation.
Bueno, A. (Álvaro)   +6 more
core   +1 more source

Treatment of hepatocellular carcinoma with portal vein tumor thrombus: advances and challenges

open access: yesOncoTarget, 2017
Portal vein tumor thrombus is a frequent, challenging complication in hepatocellular carcinoma. Hepatocellular carcinoma patients with portal vein tumor thrombus may show worse liver function, less treatment tolerance and worse prognosis than patients ...
Jin-Fang Jiang   +6 more
semanticscholar   +1 more source

Endothelial Cytotoxicity of Drug‐Doped Polypyrrole Coatings on Biodegradable Iron for Stent Applications

open access: yesAdvanced Materials Interfaces, EarlyView.
Electrochemically deposited polypyrrole coatings doped with salicylate and dexamethasone are tested on iron substrates. Their safety for biological use is confirmed in vitro with human endothelial cells. Abstract Conducting polymers, such as polypyrrole (PPy), are promising coatings for biodegradable vascular implants due to their electrical ...
Karolina Cysewska   +2 more
wiley   +1 more source

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