Results 31 to 40 of about 194,696 (300)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Sanctioning Memory: Changing Identity - Using 3D laser scanning to identify two 'new' portraits of the Emperor Nero in English antiquarian collections

Internet Archaeology, 2016
Using 3D laser scanning, two badly damaged and heavily restored Roman portraits from English country house collections are here identified as originally being representations of the Emperor Nero. The first portrait, from Petworth House, is of Nero at the
Miles Russell, Harry Manley
doaj   +1 more source

A kinship network analysis of Palmyrene genealogies

Journal of Historical Network Research, 2021
In this proof-of-concept study we investigate the potential and challenges of a formal network approach for the examination of 1st to 3rd century CE kinship networks in ancient Palmyra (in present-day Syria). The recent availability of a large, digitised
Tom Brughmans, Olympia Bobou, Nathalia B. Kristensen, Rikke R. Thomsen, Jesper V. Jensen, Eivind H. Seland, Rubina Raja   +6 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Les Sincères de Marivaux : un « Misanthrope alambiqué et restreint » ?

Etudes Epistémè
In the work of a playwright who paid no tribute to Molière, a play like Les Sincères (1739) would appear to be an exception. In Proust's words, Marivaux's brief comedy is a “convoluted and narrow Misanthrope”.
Nicolas Fréry
doaj   +1 more source

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

Arthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen, Yasuo Nagafuchi, Kristina Lend, Seyam Alemyar, Herman Kasper Glas, Gerdur Gröndal, Bjorn Gudbjornsson, Espen A. Haavardsholm, Kim Hørslev Petersen, Jon Lampa, Merete Lund Hetland, Dan Nordström, Mike Nurmohamed, Mikkel Østergaard, Anna Rudin, Marte Schrumpf Heiberg, Tuulikki Sokka‐Isler, Till Uhlig, Josien Veris‐van Dieren, Ronald van Vollenhoven, Tom Huizinga, Marcel JT Reinders, Sytske Anne Bergstra, Erik van den Akker, Rachel Knevel   +24 more
wiley   +1 more source

Criadores hispanos de caballos de carreras en el Bajo Imperio en las cartas de Símaco

Espacio, Tiempo y Forma. Serie II, Historia Antigua, 2010
Se recogen todas las menciones de caballos hispanos en los autores antiguos. Los criadores de caballos en Hispania. Las marcas de yeguadas. Los nombres de los propietarios. La exportación de caballos hispanos en el siglo II. Eran velocísimas. Retratos de
José María Blázquez Martínez
doaj   +1 more source

Homosexualita a staré umění: poznámky k interpretaci mužských renesančních portrétů

Acta Universitatis Carolinae Philosophica et Historica, 2020
The paper is concerned with the problematic of one of the aspects of the perception of the male portrait of the Renaissance. The article is a separate chapter of the master’s thesis devoted to the male portrait of friends in Italian Renaissance painting.
Ljubov Marsova
doaj   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source