Results 21 to 30 of about 27,357 (215)

Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]

, 2016
Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core   +5 more sources

Pharmacokinetics and Pharmacodynamics of Posaconazole

Drugs, 2020
Posaconazole is typically used for preventing invasive yeast and mold infections such as invasive aspergillosis in high-risk immunocompromised patients.
Lu Chen, E. Krekels, P. Verweij, Jochem B. Buil, C. Knibbe, R. Brüggemann   +5 more
semanticscholar   +1 more source

Progress of triazole antifungal agent posaconazole in individualized therapy

Journal of Clinical Pharmacy and Therapeutics, 2022
Posaconazole is the second‐generation triazole antifungal agent with widespread clinical application. Posaconazole exposure is influenced by various factors such as drug interactions, disease state and diet, resulting in a high interindividual ...
Yishuo Shu, Yinping Shi, Yilei Yang, Zhonghua Dong, Qiaoyan Yi, Haiyan Shi   +5 more
semanticscholar   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Intravenous-oral itraconazole versus oral posaconazole in preventing invasive fungal diseases for acute leukemia patients

Blood Science, 2023
Invasive fungal diseases (IFDs) are major and lethal infectious complications for patients with neutropenia after chemotherapy. Prophylaxis with intravenous and oral suspended itraconazole (200 mg Q12h intravenously × 2 days followed by 5 mg/kg·d orally ...
Li Liu, Xiaolei Pei, Runzhi Ma, Yi He, Rongli Zhang, Jialin Wei, Qiaoling Ma, Weihua Zhai, Aiming Pang, Erlie Jiang, Mingzhe Han, Donglin Yang, Sizhou Feng   +12 more
doaj   +1 more source

Factors associated with subtherapeutic levels of oral posaconazole tablet: a detailed analysis from a tertiary care center in India

International Journal of Infectious Diseases, 2022
Objectives: Posaconazole is a broad-spectrum triazole antifungal, with activity against various clinically important fungi. The delayed release (DR) tablet of posaconazole has been shown to have a superior pharmacokinetic profile in comparison with the ...
Parikshit S. Prayag, Shweta P. Panchakshari, Namita P. Mahalle, Surabhi Dhupad, Sampada A. Patwardhan, Sadanand S. Naik, Sharwari Narawade, Sameer Melinkeri, Amrita P. Prayag   +8 more
doaj   +1 more source

Pharmacokinetics and target attainment of intravenous posaconazole in critically ill patients during extracorporeal membrane oxygenation.

Journal of Antimicrobial Chemotherapy, 2021
BACKGROUND Posaconazole is an antifungal drug used for prophylaxis and treatment of invasive fungal infections. Severe influenza has been identified as a risk factor for invasive pulmonary aspergillosis in critically ill patients.
R. Van Daele, R. Brüggemann, E. Dreesen, P. Depuydt, B. Rijnders, F. Cotton, D. Fage, M. Gijsen, Kenny Van Zwam, Y. Debaveye, J. Wauters, I. Spriet   +11 more
semanticscholar   +1 more source

Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]

, 2017
This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Bellagamba, Giuseppe, Campestre, Cristina, Carradori, Simone, Celia, Christian, De Luca, Elisa, Di Marzio, Luisa, Guglielmi, Paolo, Locatelli, Marcello, Menta, Sergio, Zengin, Gokhan   +9 more
core   +3 more sources

THE EFFICACY OF POSACONAZOLE FOR PROPHYLAXIS OF INVASIVE MYCOSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

Медицинский совет, 2017
Efficacy of posaconazole for prophylaxis was evaluated in 77 chemotherapy cycles in 59 patients with acute myeloid leukemia (AML) aged 39 (17–62) years from 2012  till 2017.
G. A. Klyasova, V. A. Okhmat, E. N. Parovichnikova, E. O. Gribanova, V. V. Troitskaya, V. G. Savchenko   +5 more
doaj   +1 more source

Posaconazole‐induced hypertension in children with cystic fibrosis

Respirology Case Reports, 2021
Posaconazole is a triazole antifungal with a broad spectrum of activity against moulds including Aspergillus spp. Emerging data suggest posaconazole may be effective in the treatment of allergic bronchopulmonary aspergillosis (ABPA) complicating cystic ...
Rachael Marpole, Daniel K. Yeoh, Adelaide L. Withers   +2 more
doaj   +1 more source