Results 21 to 30 of about 13,819 (183)

THE EFFICACY OF POSACONAZOLE FOR PROPHYLAXIS OF INVASIVE MYCOSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

Медицинский совет, 2017
Efficacy of posaconazole for prophylaxis was evaluated in 77 chemotherapy cycles in 59 patients with acute myeloid leukemia (AML) aged 39 (17–62) years from 2012  till 2017.
G. A. Klyasova, V. A. Okhmat, E. N. Parovichnikova, E. O. Gribanova, V. V. Troitskaya, V. G. Savchenko   +5 more
doaj   +1 more source

Evaluation of antifungal susceptibility and clinical characteristics in fungal keratitis in a tertiary care center in North India

Indian Journal of Ophthalmology, 2022
Purpose: To study the antifungal susceptibility of common corneal pathogenic fungi to antifungal agents in the North Indian population. Methods: Prospective study of the antifungal sensitivity testing (natamycin, amphotericin B, voriconazole ...
Murugesan Vanathi, Ravinder Naik, Navneet Sidhu, Nishat Hussain Ahmed, Noopur Gupta, Radhika Tandon   +5 more
doaj   +1 more source

The Outcome of Antifungal Prophylaxis with Posaconazole in Patients with Acute Myeloid Leukemia: A Single-Center Study

Turkish Journal of Hematology, 2018
Objective: Invasive fungal infections (IFIs) are a significant cause of morbidity and mortality among neutropenic patients undergoing chemotherapy for acute myeloid leukemia (AML) and stem cell transplantation.
Vildan Özkocaman, Fahir Özkalemkaş, Serdar Seyhan, Beyza Ener, Ahmet Ursavaş, Tuba Ersal, Esra Kazak, Ezgi Demirdöğen, Reşit Mıstık, Halis Akalın   +9 more
doaj   +1 more source

Posaconazole‐induced hypertension in children with cystic fibrosis

Respirology Case Reports, 2021
Posaconazole is a triazole antifungal with a broad spectrum of activity against moulds including Aspergillus spp. Emerging data suggest posaconazole may be effective in the treatment of allergic bronchopulmonary aspergillosis (ABPA) complicating cystic ...
Rachael Marpole, Daniel K. Yeoh, Adelaide L. Withers   +2 more
doaj   +1 more source

Comparative pharmacoeconomic analysis of posaconazole therapy in tablet form and in suspension for invasive fungal infections prevention

Онкогематология, 2021
The objective of the study was to conduct a comparative pharmacoeconomic analysis of the treatment with posaconazole in a tablet form for the prevention of invasive fungal infections in patients aged 13 years and older with prolonged neutropenia and ...
I. S. Krysanov, E. V. Makarova, V. Yu. Ermakova, V. S. Krysanova, N. N. Klimko   +4 more
doaj   +1 more source

Voriconazole and posaconazole therapeutic drug monitoring: a retrospective study

Annals of Clinical Microbiology and Antimicrobials, 2017
Background Therapeutic drug monitoring (TDM) aims to minimize the clinical impact of posaconazole and voriconazole pharmacokinetic variability. However, its benefits on clinical outcomes are still being defined.
Whitley M. Yi, Kelly E. Schoeppler, Jaclyn Jaeger, Scott W. Mueller, Robert MacLaren, Douglas N. Fish, Tyree H. Kiser   +6 more
doaj   +1 more source

Effects of Posaconazole on Tacrolimus Population Pharmacokinetics and Initial Dose in Children With Crohn’s Disease Undergoing Hematopoietic Stem Cell Transplantation

Frontiers in Pharmacology, 2022
The present study explored the effects of posaconazole on tacrolimus population pharmacokinetics (PPK) in children with Crohn’s disease (CD) undergoing hematopoietic stem cell transplantation (HSCT).
Xiao Chen, Dongdong Wang, Feng Zheng, Lin Zhu, Yidie Huang, Yiqing Zhu, Ying Huang, Hong Xu, Zhiping Li   +8 more
doaj   +1 more source

Utility of posaconazole therapeutic drug monitoring and assessment of plasma concentration threshold for effective prophylaxis of invasive fungal infections: a meta-analysis with trial sequential analysis

BMC Infectious Diseases, 2018
Background Posaconazole therapeutic drug monitoring (TDM) is increasingly used in clinical practice. However, the utility of posaconazole TDM and the target of posaconazole plasma concentration for clinical successful prophylaxis remain uncertain and ...
Lu Chen, Yan Wang, Tao Zhang, Ying Li, Ti Meng, Leichao Liu, Ruifang Hao, Yalin Dong   +7 more
doaj   +1 more source

Advancing posaconazole quantification analysis with a new reverse-phase HPLC method in its bulk and marketed dosage form [version 2; peer review: 2 approved]

F1000Research, 2023
Introduction: Posaconazole is a widely used antifungal drug, and its accurate quantification is essential for quality control and assessment of its pharmaceutical products.
Srinivas Hebbar, Anup Naha, Abhishek Chaturvedi, Usha Rani, Annamalai Rama, Induja Govindan   +5 more
doaj  

Posaconazole treatment of refractory coccidioidomycosis in dogs

Journal of Veterinary Internal Medicine, 2021
Background The majority of dogs with coccidioidomycosis recover with administration of fluconazole or itraconazole, although some cases are refractory or the dogs do not tolerate administration of these medications.
Lisa F. Shubitz, Sallianne Schlacks, Polina Vishkautsan, Christine D. Butkiewicz, Kate A. Worthing   +4 more
doaj   +1 more source