Results 191 to 200 of about 3,801,176 (289)

FIGO position statement: Gamete donations. [PDF]

Int J Gynaecol Obstet
Henry L, Antsaklis A, Feldberg D, Malhotra J, Pandit S, Salazar C, Vidaeff A, Zadykowicz R, Hull ML, Purandare N, FIGO Committee on the Ethical Aspects of Human Reproduction and Women's Health and the FIGO Committee on Reproductive Medicine, Endocrinology, and Infertility.   +12 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Saudi Heart Association Position Statement on Adult Vaccinations for Patients With Cardiovascular Diseases. [PDF]

J Saudi Heart Assoc
Alhabeeb W, Farahat FM, Alshamrani MM, Aldahash R, Al-Moamary MS, Balghith M, Hanfi Y.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Reproductive carrier screening for genetic disorders: position statement of the Canadian College of Medical Geneticists. [PDF]

J Med Genet
Aul RB, Canales KE, De Bie I, Laberge AM, Langlois S, Nelson TN, Walji S, Yu AC, Lazier J, Canadian College of Medical Geneticists, Canadian College of Medical Geneticists .   +10 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

CSACI position statement: prescribing sublingual immunotherapy tablets for aeroallergens

Allergy, Asthma & Clinical Immunology, 2018
J. Quirt, R. Gagnon, A. K. Ellis, H. L. Kim   +3 more
doaj   +1 more source

APSIC revised guidelines for prevention of central line associated bloodstream infections (CLABSI): a summary and position statement. [PDF]

Antimicrob Steward Healthc Epidemiol
Ling ML, Apisarnthanarak A, Ching P, Chen YC, Harrington G, Huh JW, Jaggi N, Morikane K, Poonyathawon S.   +8 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

FelineVMA 2025 transportation of cats in motor vehicles position statement. [PDF]

J Feline Med Surg
europepmc   +1 more source