Results 171 to 180 of about 1,182,692 (300)

The Role of Physical Activity in the Prevention and Management of Obesity: A Position Statement From the World Obesity Federation. [PDF]

Obes Rev
Gowers Z, Li B, Gómez SF, Jackson-Morris A, Farmer M, Thompson R, Buse K.   +6 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Standardising the preparation for, and delivery of care during, and after critical incidents: a Faculty of Sport and Exercise Medicine position statement. [PDF]

Front Sports Act Living
Heron N, Griffin S.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Autonomy and refusal of dialysis: ethical and legal reflections based on the position statement of the Brazilian Society of Nephrology. [PDF]

J Bras Nefrol
Santos CGDS, Guirro ÚBDP, Dadalto L.
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Time to reframe osteoporosis: a position statement to characterize the osteoporosis care gap. [PDF]

JBMR Plus
Paskins Z, Bullock L, Hawarden A, Blackman F, Armstrong DJ, Bentley I, Clark EM, Daly RM, David D, Farr V, Flower D, Gregson CL, Griffin J, Hauser B, Javaid MK, Jinks C, Jones R, Kettle C, Lam E, Leyland S, McKinley J, Nicholls E, O'Neill TW, Ong Ing Wei T, Sahota O, Poole K, Ralston S, Ruggerio C, Sandhu K, Sangan C, Turnbull C, Vine N.   +31 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

UK National Screening Committee position statement on evidence required for multicancer detection tests.

BMJ
Batson S, Taylor-Phillips S, Mackie A, Given-Wilson R, Halligan S, Hackshaw A, Callender T, Hyde C, Payne K, Visintin C, Thompson D, Evans DG, Richards M, Shinkins B.   +13 more
europepmc   +1 more source

Cultural psychiatry in Flanders, Belgium: an exploratory focus group study and position statement. [PDF]

Eur Psychiatry
Willems R, Albert N, Van den Broeck K, Niemegeers P, Van Den Bossche M, Sadat Mohammad Rafael Nazari S, Claus L, Van den Ameele S, Detraux J, De Hert M, Scholar-Ocak M, Dom G, Pleysier S, Catthoor K.   +13 more
europepmc   +1 more source