Results 161 to 170 of about 3,801,176 (289)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Time to reframe osteoporosis: a position statement to characterize the osteoporosis care gap. [PDF]

JBMR Plus
Paskins Z, Bullock L, Hawarden A, Blackman F, Armstrong DJ, Bentley I, Clark EM, Daly RM, David D, Farr V, Flower D, Gregson CL, Griffin J, Hauser B, Javaid MK, Jinks C, Jones R, Kettle C, Lam E, Leyland S, McKinley J, Nicholls E, O'Neill TW, Ong Ing Wei T, Sahota O, Poole K, Ralston S, Ruggerio C, Sandhu K, Sangan C, Turnbull C, Vine N.   +31 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Patient Education in Chronic Kidney Disease: A Position Statement of the Polish Society of Nephrology. [PDF]

Int J Nephrol Renovasc Dis
Lichodziejewska-Niemierko M, Mosakowska M, Adamczak M, Naumnik B.   +3 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

FIGO position statement on surrogacy: Ethical considerations. [PDF]

Int J Gynaecol Obstet
Zadykowicz R, Watson K, Antsaklis A, FIGO Committee on Ethical Aspects of Human Reproduction and Women's Health.   +3 more
europepmc   +1 more source

Position Statements

Diabetes Care, 2010
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025. [PDF]

Rev Bras Ginecol Obstet
de Oliveira GMM, de Almeida MCC, Valério CM, Giuffrida F, Espíndola LN, Izar MCO, Marques-Santos C, Freire CMV, Albuquerque CJDM, Chagas ACP, Précoma DB, Mesquita ET, Saraiva JFK, Costa MENC, Lemke VMG, de Lucena AJG, Brandão AA, Fagundes AAP, Macedo AVS, Polanczyk CA, Leitão CB, Silveira DS, Coutinho EDR, Nahas EAP, Alexandre ERG, Campana EMG, Bragança EOV, Colombo FMC, Barbosa ICQ, Rivera IR, Kulak J, Salles JEN, de Sá JR, Soares JM, Dourado LA, Moura LZ, Magalhães LBNC, Pompei LM, Passaglia LG, Assad MHV, Rodrigues MAH, Rivera MAM, Lopes MAAAM, Paiva MSMO, de Castro ML, Campos MDSB, de Souza OF, de Medeiros OO, Freitas RAP, de Carvalho RCM, da Silva SCTF, Rodrigues TCV, Avila WS, da Silva WS, Nazima WI, da Costa-Paiva LHS, Wender MCO.   +56 more
europepmc   +1 more source