Results 71 to 80 of about 495,798 (246)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

SatDiff: A Stable Diffusion Framework for Inpainting Very High-Resolution Satellite Imagery

IEEE Access
Satellite image inpainting is a critical task in remote sensing, requiring accurate restoration of missing or occluded regions for reliable image analysis.
Teerapong Panboonyuen, Chaiyut Charoenphon, Chalermchon Satirapod   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Genetic diversity and population structure of Kudouzi (Sophora alopecuroides) in Northwest China revealed by SNP markers and seed phenotypic traits

Frontiers in Plant Science
IntroductionSophora alopecuroides L., a perennial leguminous herb native to northwest China, holds medicinal, ecological, and forage value. However, intensified human activities have caused a sharp decline in its wild populations and genetic diversity ...
Cunkai Luo, Cunkai Luo, Fanyan Ma, Fanyan Ma, Panxin Niu, Zhao Zhang, Weiting Chen, Ping Jiang, Mei Wang, Mei Wang, Guangming Chu, Guangming Chu, Xiang Huang, Xiang Huang   +13 more
doaj   +1 more source

Positioning Hate

Journal of Hate Studies, 2004
A year after the publication of my book on women in the contemporary organized racist movement,Inside Organized Racism: Women in the Hate Movement (2002), I received a series of emails from a woman I will call Jenny. The study of racist activists in this book was based in part on my interviews with women in the Ku Klux Klan, neo-Nazi and white ...
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Survey on positioning technology based on signal of opportunity from low earth orbit

Frontiers in Physics
Positioning, Navigation, and Timing (PNT) services are essential for supporting various aspects of modern society. Fields such as communications, transportation, and military operations heavily rely on accurate and reliable PNT services, with this ...
Jiawei He, Jiawei He, Shaojie Ni, Shaojie Ni, Honglei Lin, Honglei Lin, Zhe Liu, Zhe Liu, Zhibin Xiao, Zhibin Xiao   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

GuidedBox: a segmentation-guided box teacher-student approach for weakly supervised road segmentation

European Journal of Remote Sensing
The importance of road segmentation in remote sensing data cannot be overstated, as it underpins various critical applications such as urban planning, traffic monitoring and autonomous driving systems.
Teerapong Panboonyuen, Chaiyut Charoenphon, Chalermchon Satirapod   +2 more
doaj   +1 more source