Results 91 to 100 of about 327,560 (267)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Mobile Robots: Trajectory Analysis, Positioning and Control

Applied Sciences
The rapid evolution of mobile robotics over the last decade has reshaped the landscape of technology and its applications in society [...]
Juan Ernesto Solanes, Luis Gracia
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Root characteristics and soil microbial entropy can be important indicators of degradation of Populus simonii in sandy areas

Global Ecology and Conservation
Forests play a key role in global carbon sequestration, biodiversity conservation and ecological security, and their degradation weakens essential services such as wind breaking and sand fixation, especially in shelterbelts of arid and semi-arid sandy ...
Xue Chen, Haibing Wang, Hejun Zuo, Jin Ni, Min Yan, Haoqing Yang, Yunfei Bai   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Periphytic biofilm at saline soil-water interface captured more cadmium than at non-saline ones: process, mechanism, and implication

Environmental Chemistry and Ecotoxicology
Soil salinity inhibits rice growth and enhances cadmium (Cd) mobility, threatening rice production and human health. Periphytic biofilm (PB), widely distributed at the soil-water interface of paddy filed, exhibits strong Cd capture capability.
Lingyuan Chen, Wanying Li, Shuai Pan, Yanyun Han, Dongmei Zhou, Yinlong Zhang, Junzhuo Liu, Yonghong Wu, Jiangang Han, Imran Ali, Haiying Lu   +10 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Mechanism of mobile robot with positioning system

Nihon Kikai Gakkai ronbunshu
This paper presents the development and evaluation of a Mechanical Positioned Guided Vehicle (MPGV), a sensorless and mechanical-control mobile robot designed to achieve high-precision positioning of less than ±5 mm.
Yuta WAKABAYASHI, Ryotaro KAYAWAKE
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source