Results 101 to 110 of about 10,064,891 (293)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

RFID Positioning

, 2012
This chapter investigates the techniques and algorithms for low-cost and portable ubiquitous indoor/outdoor personal positioning systems that use Radio Frequency Identification (RFID) based multi-sensor integration.
Retscher, Günther, Zhang, Kefei, Zhu, Ming   +2 more
core   +4 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Grid Residual Tropospheric Corrections for Improved Differential GPS Positioning Over the Victoria GPS Network (GPSnet)

, 2004
. Tropospheric delay is one of the major error sources in GPS positioning. The delay of radio signals caused by the troposphere can range from 2 m at the zenith to 20 m at lower elevation angles.
Yanming Feng, Yi Zheng, Zheng, Yi, Zhengdong Bai, Feng, Yanming, Bai, Zhengdong   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Control of Wafer Scanners: Methods and Developments

, 2020
In this tutorial paper, control design aspects of wafer scanners used in the semiconductor industry will be highlighted. At the same time, challenges for control design development as to meet the ever increasing demands on accuracy and speed are ...
Ahlawat, R., J. Simonelli, Butler, Hans, Simonelli, J., van der Meulen, S.H., K. O'Brien, Dirkx, N.J., Teng, K-T., Zhao, Y., R. Ahlawat, H. Butler, S.H. van der Meulen, Y. Zhao, N.J. Dirkx, Heertjes, Marcel F., K-T. Teng, O'Brien, K., M.F. Heertjes   +17 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Mobile Robots: Trajectory Analysis, Positioning and Control

Applied Sciences
The rapid evolution of mobile robotics over the last decade has reshaped the landscape of technology and its applications in society [...]
Juan Ernesto Solanes, Luis Gracia
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source