Results 251 to 260 of about 226,151 (328)

Targeted Delivery of CNS‐Specific Hesperidin as a Leptin Sensitizer for Treating Obesity‐Associated Sleep‐Disordered Breathing

Advanced Science, EarlyView.
Hesperidin nanoparticles (HE NPs) effectively combat obesity and sleep‐disordered breathing in mice by enhancing leptin sensitivity. Through suppression of hypothalamic endoplasmic reticulum stress and restoration of leptin signaling, HE NPs promote weight loss and improve breathing during sleep.
Yixuan Wang, Qingyu Zhao, Qingfeng Zhang, Xiaofeng Wu, Xu Liu, Shujuan Wu, Hailing Liu, Beini Zhou, Shiqian Zha, Dong Zhao, Gang Deng, Ke Hu   +11 more
wiley   +1 more source

Exploring biogeochemical transformation in a hypertrophic lake with dual focus on environmental cues and potential functional fingerprints of littoral bacteria. [PDF]

Sci Rep
Dashora M, Kumar M, Kaushik G, Kumar A.
europepmc   +1 more source

PPP1R3B Suppresses Atherosclerosis by Promoting the M2 Polarization of Macrophages Through Glycogen Metabolic Reprogramming

Advanced Science, EarlyView.
PPP1R3B induces anti‐inflammatory M2 macrophage polarization and maintains energy supply in plaques. Its absence accelerates plaque progression. PPP1R3B regulates M2 macrophage polarization and energy metabolism via phosphorylated STAT3 (p‐STAT3), which plays a dual role by activating anti‐inflammatory transcriptional programs through the PPAR‐γ/PGC‐1α/
Lin Shen, Junchao Yu, Weiqian Chen, Yanran Bi, Zhangyu Yang, Chenying Lu, Chengli Jiang, Yang Yang, Minjiang Chen, Jianhua Zou, Lingchun Lv, Xiaoyuan Chen, Jiansong Ji   +12 more
wiley   +1 more source

Global carbon flux dataset generated by fusing remote sensing and multiple flux networks observation. [PDF]

Sci Data
Yuan Q, Wang X, Che T, Li J.
europepmc   +1 more source

EFFECTIVENESS OF EARLY USE OF SPONTANEOUS RESPIRATION UNDER CONTINUOUS POSITIVE AIRWAY PRESSURE IN PREMATURE INFANTS WITH VERY LOW BODY WEIGHT AT BIRTH

, 2017
Satsita S. Khasanova, A. L. Batmanov
openalex   +2 more sources

Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector

Advanced Science, EarlyView.
Aphids release salivary protein GLD into plants, which induces ROS in the phloem. This leads to the intermolecular disulfide bonds formation among SEO proteins, promoting their transition from the dispersed state to the aggregated state. SEO can interact with CMV CP.
Huijuan Guo, Qingyun Shi, Xiaoyu Ling, Yuting Wu, Lin He, Danyang Li, Keyan Zhu‐Salzman, Yucheng Sun   +7 more
wiley   +1 more source

Human Stress Classification Using Cardiovascular and Respiratory Data Based on Machine Learning Techniques. [PDF]

J Med Signals Sens
Yaghoubi M, Adib N, Monfared AR, Tondashti SA, Akhavan S.   +4 more
europepmc   +1 more source

Effects of warming and ocean acidification on calcification and photosynthesis of Arctic coralline red algae under summer light conditions [PDF]

, 2012
Hellemann, Dana
core  

PM2.5 Induce Endothelial‐Mesenchymal Transition and Cardiac Fibrosis via the NCOA4‐Mediated Ferritinophagy

Advanced Science, EarlyView.
This study primarily reveals that PM2.5‐derived Fe‐containing particles, particularly magnetite, are specifically enriched in the heart. Here, they interact with NCOA4 in endothelial cells, disrupt iron homeostasis by enhancing ferritinophagy, and subsequently trigger the process of EndMT through the NCOA4/KLF5 pathway.
Qinglin Sun, Mengyuan Wang, Lin Liu, Ruiyang Ding, Kanglin Yan, Shiqian Liu, Xiaoke Ren, Qing Xu, Zhiwei Sun, Qian Liu, Yi Yang, Junchao Duan   +11 more
wiley   +1 more source

Freeze-thaw seasonal variations and environmental controls of CO₂ and CH₄ diffusive emissions from reservoirs in the upper Yellow River. [PDF]

Sci Rep
Li C, Wu W, Chen H, Ren L, Kang X.
europepmc   +1 more source