Results 41 to 50 of about 320,316 (321)

Effect of Positive End-Expiratory Pressure on Central Venous Pressure in Patients under Mechanical Ventilation

Archives of Academic Emergency Medicine, 2018
Introduction: Finding the probable governing pattern of PEEP and CVP changes is an area of interest for in-charge physicians and researchers. Therefore, the present study was designed with the aim of evaluating the relationship between the mentioned ...
Majid Shojaee, Anita Sabzghabaei, Hossein Alimohammadi, Hojjat Derakhshanfar, Afshin Amini, Bahareh Esmailzadeh   +5 more
doaj   +1 more source

Safety in intrahospital transportation: evaluation of respiratory and hemodynamic parameters. A prospective cohort study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Intrahospital transportation of mechanically ventilated patients is a high-risk situation. We aimed to determine whether transfers could be safely performed by using a transportation routine.
Bruno Franco Mazza, José Luiz Gomes do Amaral, Heloisa Rosseti, Rosana Borges Carvalho, Ana Paula Resque Senna, Hélio Penna Guimarães, Flavia Ribeiro Machado   +6 more
doaj   +1 more source

Early Open-Lung Ventilation Improves Clinical Outcomes in Patients with Left Cardiac Dysfunction Undergoing Off-Pump Coronary Artery Bypass: a Randomized Controlled Trial

Brazilian Journal of Cardiovascular Surgery
Objective: To compare pulmonary function, functional capacity and clinical outcomes amongst three groups of patients with left ventricular dysfunction following off-pump coronary artery bypass, namely: 1) conventional mechanical ventilation (CMV); 2 ...
Douglas W. Bolzan, Walter José Gomes, Isadora S. Rocco, Marcela Viceconte, Mara L. S. Nasrala, Hayanne O. Pauletti, Rita Simone L. Moreira, Nelson A. Hossne Jr, Ross Arena, Solange Guizilini   +9 more
doaj   +1 more source

HIGH FLOW OXYGEN THERAPY MACHINE USING HIGH FLOW NASAL CANNULATION A HOPE FOR COVID-19 PATIENTS IN ACUTE RESPIRATORY FAILURE

Liaquat Medical Research Journal, 2021
OBJECTIVE: To provide humidified, heated and precis oxygen with high efficiency of   Functional residual to acute respiratory distress syndrome patients caused by COVID-19.
Ali Raza Khoso
doaj  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

Oman Medical Journal, 2023
Objectives: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.
Abdul Hakeem Al Hashim, Ibrahim Al Zakwani, Abdullah Al Jadidi, Ruqaiya Al Harthi, Maadh Al Naabi, Ramakrishna Biyappu, Sonali Kodange, Naveen Kumar Asati, Tamadher Al Barhi, Mudhun Mohan, Jayachandiran Jagadeesan, Micheline Sachez, Praisemabel S. Sycaayao, Khalfan Al Amrani, Huda Al Khalili, Rashid Al Mamari, Mujahid Al-Busaidi   +16 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Pressure- vs. volume-controlled ventilation and their respective impact on dynamic parameters of fluid responsiveness: a cross-over animal study

BMC Anesthesiology, 2023
Background and goal of study Pulse pressure variation (PPV) and stroke volume variation (SVV), which are based on the forces caused by controlled mechanical ventilation, are commonly used to predict fluid responsiveness.
Amelie Zitzmann, Tim Bandorf, Jonas Merz, Fabian Müller-Graf, Maria Prütz, Paul Frenkel, Susanne Reuter, Brigitte Vollmar, Nora A. Fuentes, Stephan H. Böhm, Daniel A. Reuter   +10 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

A method for improving recognition of lying postures using a measured signal intensity of respiration and heartbeat

Nihon Kikai Gakkai ronbunshu, 2018
We describe a method for improving recognition of lying postures using a measured signal intensity of respiration and heartbeat. We have proposed a measurement method of lying posture, respiration, and heartbeat using a Smart Rubber sensor, a rubber ...
Kazuya MATSUO, Toshiharu MUKAI, Shijie GUO   +2 more
doaj   +1 more source