Results 241 to 250 of about 4,995,094 (293)

Positive Allosteric Modulators of Opioid Receptors

2016
Activation of opioid receptors produces powerful analgesia; and µ-opioid receptor agonists such as morphine and oxycodone remain the “gold standard” for pain therapy, despite their abuse liability and dangerous side effect profile. Safer pain medications are urgently needed.
Kristin L. Rockwell, Andrew Alt
openaire   +1 more source

Reprogramming CBX8-PRC1 function with a positive allosteric modulator

Cell Chemical Biology, 2022
Dongxu Li, Dmitri B Kireev, Daniel Bsteh
exaly  

mGluR5 positive allosteric modulators

Drugs of the Future, 2008
null Chen, Y., null Conn, P.J.
openaire   +1 more source

SK CHANNEL POSITIVE ALLOSTERIC MODULATORS

2023
ZHANG MIAO, PARANG KEYKAVOUS, IBRAHIM NAGLAA, NAM YOUNG WOO, BEZPROZVANNY ILYA, CUI MENG   +5 more
openaire   +2 more sources

Anti-parkinsonian effect of the mGlu positive allosteric modulator LY-487,379 as monotherapy and adjunct to a low L-DOPA dose in the MPTP-lesioned marmoset

European Journal of Pharmacology, 2023
Imane Frouni, Adjia Hamadjida, Cynthia Kwan   +2 more
exaly  

Positive Allosteric Modulators of MGLUR2

2013
MATTSON RONALD J, MENG ZHAOXING, GUERNON LEATTE R   +2 more
openaire   +6 more sources

TrkB POSITIVE ALLOSTERIC MODULATORS

2021
ROGNAN DIDIER, SCHMITT MARTINE, CAZORLA MAXIME   +2 more
openaire   +1 more source

POSITIVE ALLOSTERIC MODULATORS OF MGLUR2

2011
LAYTON MARK E, KELLY MICHAEL J, HARTINGH TIMOTHY J   +2 more
openaire   +10 more sources

Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA receptor positive allosteric modulator

Neuropharmacology, 2020
Paul A. Davies, Francesco G Salituro, Amit Modgil   +2 more
exaly  

Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies

Journal of Psychopharmacology, 2015
Luc van Nueten
exaly