Results 261 to 270 of about 4,995,094 (293)

Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator

European Journal of Pharmacology, 2011
Jeffrey S Smith, Patricia Schroeder
exaly  

Efficient One-Pot Synthesis of the GABAB Positive Allosteric Modulator (R,S)-5,7-Di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one

Synthetic Communications, 2008
Andrew W Thomas, Pari Malherbe, Roger D Norcross   +2 more
exaly  

POSITIVE ALLOSTERIC MODULATORS AND SILENT ALLOSTERIC MODULATORS OF THE Mu OPIOID RECEPTOR

2014
BURFORD NEIL, ALT ANDREW
openaire   +3 more sources

Discovery of a selective M positive allosteric modulator based on the 3-amino-thieno[2,3-]pyridine-2-carboxamide scaffold: Development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia

Bioorganic and Medicinal Chemistry Letters, 2013
Thomas M Bridges, Craig W. Lindsley, Jeffrey Conn   +2 more
exaly  

POSITIVE ALLOSTERIC MODULATORS FOR MELANOCORTIN RECEPTORS

2013
CONE ROGER D, SEBAG JULIEN A, PANTEL JACQUES, WILLIAMS SAVANNAH Y, WEAVER DAVID C, SULIKOWSKI GARY A, LINDSLEY CRAIG W, PORTONOVA PADMA S, ZHANG CHAO   +8 more
openaire   +3 more sources

A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain

Neuropharmacology, 2017
Matthew Volgraf, Benjamin D Sellers, Tzu-Ming Wang   +2 more
exaly  

QUINOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

2007
SHIPE WILLIAM D, LINDSLEY CRAIG, HALLETT DAVID   +2 more
openaire   +5 more sources

B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor

European Journal of Pharmacology, 2017
Ivar M Mcdonald, Thaddeus F Molski, Michael K Ahlijanian   +2 more
exaly  

Discovery of a potent and brain penetrant mGluR5 positive allosteric modulator

Bioorganic and Medicinal Chemistry Letters, 2009
exaly  

Discovery of -(4-methoxy-7-methylbenzo[]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M) receptor

Bioorganic and Medicinal Chemistry Letters, 2012
Thomas M Bridges, Craig W. Lindsley, Michael W Wood   +2 more
exaly